Table 3 Genetic associations with VEGFR levels in baseline plasma and angiogram measurements

n

TT

n

TA

n

AA

p

Age (years)

1141

66.5 ± 0.37

758

70.0 ± 0.43

136

66.3 ± 1.02

0.646

Male Gender (F/M)

1141

823 (72.1%)

758

530 (69.9%)

136

106 (77.9%)

0.143

sFlt-1 (pg/ml)

284

106(100–112)

188

104(96.8–111)

27

132(110–157)

0.044

sKDR (pg/ml)

121

11,049 ± 235

75

10,799 ± 299

15

9255 ± 668

0.038

Brandt Score

580

3.26 ± 0.13

384

3.39 ± 0.16

69

3.70 ± 0.45

0.519

n

CC

n

CT

n

TT

p

Age (years)

807

66.9 ± 43

929

66.6 ± 0.40

284

66.3 ± 0.75

0.771

Male Gender Gender

807

595 (73.7%)

929

656 (70.6%)

284

195 (68.7%)

0.178

sFlt-1 (pg/ml)

222

124 ± 4.50

224

112 ± 3.80

50

119 ± 9.06

0.277

sKDR (pg/ml)

90

11,100 ± 307

77

10,500 ± 277

18

10,300 ± 643

0.290

Brandt Score

427

3.19 ± 0.15

457

3.35 ± 0.15

135

3.86 ± 0.30

0.054