Table 1 Clinical characteristics, medical treatment and coronary revascularization procedures at enrollment in the entire population stratified by the first clinical presentation of IHD (Angina vs unheralded Myocardial infarction)
Total 2772 | Angina (1353) | Myocardial Infarction (1419) | p-value | |
|---|---|---|---|---|
Sex males, N(%) | 2250 (81) | 1033 (76) | 1217 (86) | 0.001 |
Age at disease onset (yrs) | 55 ± 9 | 56 ± 9 | 54 ± 9 | < 0.001 |
Age at hospitalization (yrs) | 59 ± 8 | 60 ± 7 | 58 ± 8 | < 0.001 |
IHD Family history, N(%) | 1411 (51) | 716 (53) | 695 (49) | 0.038 |
Smoking, N(%) | 1588 (57) | 656 (49) | 932 (66) | < 0.001 |
Obesity, N(%) | 795 (29) | 400 (30) | 395 (28) | 315 |
BMI, mean ± SD | 27.5 | 28 ± 4 | 27 ± 4 | 0.363 |
Diabetes, N(%) | 576 (21) | 273 (20) | 303 (21) | 0.446 |
Hypertension, N(%) | 1439 (52) | 779 (58) | 660 (47) | 0.001 |
Hypercholesterolemia, N(%) | 1923 (69) | 954 (71) | 969 (68) | 0.204 |
Hypertriglyceridemia, N(%) | 735 (27) | 365 (27) | 370 (26) | 0.591 |
Glycaemia, mean ± SD | 111 ± 49 | 107 ± 38 | 115 ± 57 | < 0.001 |
Systolic Blood Pressure | 133 ± 21 | 136 ± 20 | 130 ± 22 | < 0.001 |
Diastolic Blood Pressure | 76 ± 11 | 76 ± 11 | 75 ± 12 | < 0.001 |
Total Cholesterol mean ± SD | 198 ± 46 | 204 ± 45 | 193 ± 47 | < 0.001 |
HDL | 41 ± 15 | 43 ± 15 | 39 ± 16 | < 0.001 |
LDL | 123 ± 45 | 129 ± 49 | 118 ± 40 | < 0.001 |
Triglycerides | 146 ± 97 | 147 ± 96 | 146 ± 98 | 0.825 |
Previous CABG, N(%) | 194 (7) | 61 (5) | 133 (9) | < 0.001 |
Previous PCI, N(%) | 382 (14) | 146 (11) | 236 (17) | < 0.001 |
Coronary Atherosclerosis | 1.47 ± 1.03 | 1.31 ± 1.05 | 1.64 ± 0.94 | < 0.001 |
EF% | 53 ± 10 | 57 ± 7 | 49 ± 11 | < 0.001 |
Medications (%) | ||||
Anti-platelet agents | 2371 (86) | 1108 (82) | 1263 (89) | < 0.001 |
Calcium channel blockers | 832 (30) | 502 (37) | 330 (23) | < 0.001 |
Nitrates | 1792 (65) | 830 (61) | 962 (68) | < 0.001 |
ACE Inhibitors | 943 (34) | 332 (25) | 611 (43) | < 0.001 |
Betablockers | 1320 (48) | 543 (40) | 777 (55) | < 0.001 |
Statins | 1514 (55) | 706 (52) | 808 (57) | 0.011 |
Antidiabetics | 429 (16) | 202 (15) | 227 (16) | 0.437 |