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Table 4 Agreement between native T1 thresholding techniques and FWHM to define extent of myocardial fibrosis

From: Defining myocardial fibrosis in haemodialysis patients with non-contrast cardiac magnetic resonance

Native T1 threshold/technique (standard deviation above normal for native T1)

Extent of fibrosis defined by FWHM (%)

Extent of fibrosis defined by technique (%)

Correlation between FWHM and T1 technique (r)

Agreement between extent of MF defined by T1 thresholding technique and FWHM (ICC)

1149 ms (2SD)

14.38 ± 1.5

44.6 ± 33.7*

0.07

0.06

1182 ms (3SD)

14.38 ± 1.5

32.8 ± 32.6*

0.1

0.07

1215 ms (4SD)

14.38 ± 1.5

22.9 ± 26.3

0.11

0.11

1248 ms (5SD)

14.38 ± 1.5

13.3 ± 17.3

0.15

0.2

1281 ms (6SD)

14.38 ± 1.5

6.7 ± 10*

0.21

0.26

1314 ms (7SD)

14.38 ± 1.5

3.5 ± 5*

0.23

0.16

1357 ms (8SD)

14.38 ± 1.5

1.8 ± 2.3*

0.17

0.05

1380 ms (9SD)

14.38 ± 1.5

1 ± 1.3*

0.02

0.03

T11SD

14.38 ± 1.5

18.24% ± 1.4*

0.55†

0.64††

Native T1 threshold/technique (standard deviation above normal for native T1)

Extent of fibrosis defined by LGE 3SD (%)

Extent of fibrosis defined by technique (%)

Correlation between LGE 3SD and T1 technique (r)

Agreement between extent of MF defined by T1 thresholding technique and LGE 3SD (ICC)

1149 ms (2SD)

21.1 ± 12.1

44.6 ± 33.7*

0.03

0.04

1182 ms (3SD)

21.1 ± 12.1

32.8 ± 32.6*

0.075

0.1

1215 ms (4SD)

21.1 ± 12.1

22.9 ± 26.3

0.11

0.18

1248 ms (5SD)

21.1 ± 12.1

13.3 ± 17.3

0.09

0.18

1281 ms (6SD)

21.1 ± 12.1

6.7 ± 10*

0.08

0.16

1314 ms (7SD)

21.1 ± 12.1

3.5 ± 5*

0.11

0.17

1357 ms (8SD)

21.1 ± 12.1

1.8 ± 2.3*

0.19

0.15

1380 ms (9SD)

21.1 ± 12.1

1 ± 1.3*

0.26

0.12

T11SD

21.1 ± 12.1

18.24% ± 1.4

0.1

0.2

  1. Abbreviations: FWHM Full width half maximum, ICC intra-class correlation coefficient, ms milliseconds, SD Standard deviation. *denotes significant difference between native T1 threshold technique for extent of fibrosis and extent of fibrosis defined by FWHM (P < 0.05). †denotes significant correlation between FWHM and native T1 thresholding technique (P < 0.05). ††denotes significant agreement between FWHM and native T1 thresholding technique (P < 0.05)