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Table 4 Agreement between native T1 thresholding techniques and FWHM to define extent of myocardial fibrosis

From: Defining myocardial fibrosis in haemodialysis patients with non-contrast cardiac magnetic resonance

Native T1 threshold/technique (standard deviation above normal for native T1) Extent of fibrosis defined by FWHM (%) Extent of fibrosis defined by technique (%) Correlation between FWHM and T1 technique (r) Agreement between extent of MF defined by T1 thresholding technique and FWHM (ICC)
1149 ms (2SD) 14.38 ± 1.5 44.6 ± 33.7* 0.07 0.06
1182 ms (3SD) 14.38 ± 1.5 32.8 ± 32.6* 0.1 0.07
1215 ms (4SD) 14.38 ± 1.5 22.9 ± 26.3 0.11 0.11
1248 ms (5SD) 14.38 ± 1.5 13.3 ± 17.3 0.15 0.2
1281 ms (6SD) 14.38 ± 1.5 6.7 ± 10* 0.21 0.26
1314 ms (7SD) 14.38 ± 1.5 3.5 ± 5* 0.23 0.16
1357 ms (8SD) 14.38 ± 1.5 1.8 ± 2.3* 0.17 0.05
1380 ms (9SD) 14.38 ± 1.5 1 ± 1.3* 0.02 0.03
T11SD 14.38 ± 1.5 18.24% ± 1.4* 0.55† 0.64††
Native T1 threshold/technique (standard deviation above normal for native T1) Extent of fibrosis defined by LGE 3SD (%) Extent of fibrosis defined by technique (%) Correlation between LGE 3SD and T1 technique (r) Agreement between extent of MF defined by T1 thresholding technique and LGE 3SD (ICC)
1149 ms (2SD) 21.1 ± 12.1 44.6 ± 33.7* 0.03 0.04
1182 ms (3SD) 21.1 ± 12.1 32.8 ± 32.6* 0.075 0.1
1215 ms (4SD) 21.1 ± 12.1 22.9 ± 26.3 0.11 0.18
1248 ms (5SD) 21.1 ± 12.1 13.3 ± 17.3 0.09 0.18
1281 ms (6SD) 21.1 ± 12.1 6.7 ± 10* 0.08 0.16
1314 ms (7SD) 21.1 ± 12.1 3.5 ± 5* 0.11 0.17
1357 ms (8SD) 21.1 ± 12.1 1.8 ± 2.3* 0.19 0.15
1380 ms (9SD) 21.1 ± 12.1 1 ± 1.3* 0.26 0.12
T11SD 21.1 ± 12.1 18.24% ± 1.4 0.1 0.2
  1. Abbreviations: FWHM Full width half maximum, ICC intra-class correlation coefficient, ms milliseconds, SD Standard deviation. *denotes significant difference between native T1 threshold technique for extent of fibrosis and extent of fibrosis defined by FWHM (P < 0.05). †denotes significant correlation between FWHM and native T1 thresholding technique (P < 0.05). ††denotes significant agreement between FWHM and native T1 thresholding technique (P < 0.05)