Table 3 Two-tailed T-test before and after OM infusion on LV function after 2 months of AR in a rat model (n = 7)
Before infusion | After infusion | p-value | |
|---|---|---|---|
Heart Rate (beats/min) | 253 ± 22 | 207 ± 35 | 0.091 |
Left Atrium (mm) | 6.2 ± 0.8 | 5.5 ± 0.7 | 0.037 |
LVEDD (mm) | 11.6 ± 1.09 | 9.0 ± 1.51 | 0.003 |
LVESD (mm) | 7.8 ± 0.91 | 5.4 ± 1.30 | 0.009 |
FS (%) | 32.1 ± 3.4 | 41.1 ± 5.3 | 0.004 |
EF (%) | 65.0 ± 4.7 | 76.6 ± 5.8 | 0.002 |
Stroke Volume (ml) | 0.19 ± 0.06 | 0.36 + 0.11 | 0.011 |
Cardiac Output (ml/min) | 44 ± 16 | 76 ± 14 | 0.027 |
SWTs (mm) | 2.67± 0.48 | 3.33 ± 0.51 | 0.390 |
SWTd (mm) | 1.6 ± 0.17 | 2.4 ± 0.39 | 0.274 |
Systolic time (ms) | 133 ± 7 | 147 ± 8 | 0.003 |
Diastolic time (ms) | 127 ± 16 | 141 ± 33 | 0.384 |
PEP (ms) | 25.0 ± 2.3 | 22.4 ± 1.8 | 0.042 |
LVET (ms) | 108 ± 6 | 125 ± 9 | 0.002 |
PEP/LVET | 0.23 ± 0.02 | 0.18 ± 0.02 | 0.007 |
Systolic time/RR | 0.51 ± 0.04 | 0.52 ± 0.06 | 0.735 |