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Table 1 Baseline characteristics of patients without and those with obstructive coronary artery disease

From: A simple prediction model to estimate obstructive coronary artery disease

Variables No (%) of patients with available data Subjects without
coronary stenosis
≥50%(n = 317)
Subjects with
coronary stenosis
≥50% (n = 945)
P value
Demographic
Age 1262(100) 62.0 ± 10.4 64.2 ± 10.2 < 0.001
Gender, men 1262(100) 181(57.1%) 693(73.3%) < 0.001
Signs and measurement
Heart rate, beats/min 1261(99.9) 73.4 ± 11.3 72.9 ± 11.9 0.49
Systolic BP, mm Hg 1262(100) 131.9 ± 17.9 132.7 ± 18.6 0.54
Diastolic BP, mm Hg 1262(100) 78.3 ± 12 77.5 ± 11.6 0.32
Weight, kg 1257(99.6) 63.5 ± 9.5 65.2 ± 10.9 0.01
Medical history
Smoking 1262 (100) 80(26.2%) 347 (36.7%) < 0.001
Hypertension 1262(100) 152(48.0%) 615 (65.1%) < 0.001
Congestive heart failure 1262(100) 19(6.5%) 79 (8.4%) 0.29
Diabetes mellitus 1260(99.8) 51(16.1%) 259 (27.5%) < 0.001
Hyperlipidemia 1262(100) 42(13.3%) 144 (15.2%) 0.75
Anemia 1262(100) 79(25.2%) 349 (37.5%) < 0.001
Medications
ACEI/ARB 1262(100) 240(75.7%) 864(89.5%) < 0.001
Diuretics 1261(99.9) 36(11.4%) 91(9.6%) 0.38
β-blocker 1262(100) 244(76.9%) 853(90.0%) < 0.001
Statin 1262(100) 279 (88.0%) 912(96.5%) < 0.001
Calcium-channel blocker 1259(99.8) 60(19.0%) 198(21.0%) 0.44
Physical examination
LVEF, % 1013(80.3) 64.6 ± 11 61.4 ± 11.9 < 0.001
Laboratory measures
Total cholesterol, mg/dl 1262(100) 168.2 ± 38.8 172.6 ± 64.6 0.15
HDL-C,mg/dl 1262(100) 40 ± 10.8 36.8 ± 10.3 < 0.001
Triglyceride, μmol/l 1262(100) 2.3 ± 11.8 1.6 ± 1.4 0.27
LDL cholesterol, μmol/l 1262(100) 2.5 ± 0.8 2.6 ± 0.9 0.19
Lp (a), μmol/l 1081(85.7) 211.4 ± 231.1 287.2 ± 311.4 < 0.001
Blood urea nitrogen, mg/dl 1246(98.7) 4.7 ± 1.6 5.2 ± 2.3 < 0.001
Serum Creatinine, μmol/l 1261(99.9) 78.0 ± 29.6 89.7 ± 50.7 < 0.001
Hemoglobin, g/ml 1246(100) 135.1 ± 15.1 133.3 ± 16.0 0.0929
Serum albumin, g/l 1220(96.7) 36.9 ± 4.1 36.1 ± 3.9 0.0035
Urine PH 1213(96.1) 5.9 ± 0.7 6.0 ± 0.7 0.48
HbA1c, % 1043(82.6) 6.3 ± 1.1 6.5 ± 1.2 0.006
Hs-CRP, mmol/l 849(67.3) 3.8 ± 5.7 6.6 ± 13.0 < 0.001
Uric acid, mmol/l 994(78.8) 364.6 ± 92.7 389.3 ± 102.5 < 0.001
B-type natriuretic peptide, pg/m 1041(82.5) 609.4 ± 2061.0 772.4 ± 2289.0 0.29
  1. LVEF = left ventricular ejection fraction; ACEI/ARB = angiotensin-converting enzyme inhibitor/angiotensin receptor blocker; HDL-C = high-density lipoprotein cholesterol; LDL-C = low-density lipoprotein-cholesterol; HbA1c = glycated hemoglobin; Hs-CRP = high-sensitivity C-reactive protein