Table 1 Baseline characteristics of patients without and those with obstructive coronary artery disease
From: A simple prediction model to estimate obstructive coronary artery disease
Variables | No (%) of patients with available data | Subjects without coronary stenosis ≥50%(n = 317) | Subjects with coronary stenosis ≥50% (n = 945) | P value |
|---|---|---|---|---|
Demographic | ||||
Age | 1262(100) | 62.0 ± 10.4 | 64.2 ± 10.2 | < 0.001 |
Gender, men | 1262(100) | 181(57.1%) | 693(73.3%) | < 0.001 |
Signs and measurement | ||||
Heart rate, beats/min | 1261(99.9) | 73.4 ± 11.3 | 72.9 ± 11.9 | 0.49 |
Systolic BP, mm Hg | 1262(100) | 131.9 ± 17.9 | 132.7 ± 18.6 | 0.54 |
Diastolic BP, mm Hg | 1262(100) | 78.3 ± 12 | 77.5 ± 11.6 | 0.32 |
Weight, kg | 1257(99.6) | 63.5 ± 9.5 | 65.2 ± 10.9 | 0.01 |
Medical history | ||||
Smoking | 1262 (100) | 80(26.2%) | 347 (36.7%) | < 0.001 |
Hypertension | 1262(100) | 152(48.0%) | 615 (65.1%) | < 0.001 |
Congestive heart failure | 1262(100) | 19(6.5%) | 79 (8.4%) | 0.29 |
Diabetes mellitus | 1260(99.8) | 51(16.1%) | 259 (27.5%) | < 0.001 |
Hyperlipidemia | 1262(100) | 42(13.3%) | 144 (15.2%) | 0.75 |
Anemia | 1262(100) | 79(25.2%) | 349 (37.5%) | < 0.001 |
Medications | ||||
ACEI/ARB | 1262(100) | 240(75.7%) | 864(89.5%) | < 0.001 |
Diuretics | 1261(99.9) | 36(11.4%) | 91(9.6%) | 0.38 |
β-blocker | 1262(100) | 244(76.9%) | 853(90.0%) | < 0.001 |
Statin | 1262(100) | 279 (88.0%) | 912(96.5%) | < 0.001 |
Calcium-channel blocker | 1259(99.8) | 60(19.0%) | 198(21.0%) | 0.44 |
Physical examination | ||||
LVEF, % | 1013(80.3) | 64.6 ± 11 | 61.4 ± 11.9 | < 0.001 |
Laboratory measures | ||||
Total cholesterol, mg/dl | 1262(100) | 168.2 ± 38.8 | 172.6 ± 64.6 | 0.15 |
HDL-C,mg/dl | 1262(100) | 40 ± 10.8 | 36.8 ± 10.3 | < 0.001 |
Triglyceride, μmol/l | 1262(100) | 2.3 ± 11.8 | 1.6 ± 1.4 | 0.27 |
LDL cholesterol, μmol/l | 1262(100) | 2.5 ± 0.8 | 2.6 ± 0.9 | 0.19 |
Lp (a), μmol/l | 1081(85.7) | 211.4 ± 231.1 | 287.2 ± 311.4 | < 0.001 |
Blood urea nitrogen, mg/dl | 1246(98.7) | 4.7 ± 1.6 | 5.2 ± 2.3 | < 0.001 |
Serum Creatinine, μmol/l | 1261(99.9) | 78.0 ± 29.6 | 89.7 ± 50.7 | < 0.001 |
Hemoglobin, g/ml | 1246(100) | 135.1 ± 15.1 | 133.3 ± 16.0 | 0.0929 |
Serum albumin, g/l | 1220(96.7) | 36.9 ± 4.1 | 36.1 ± 3.9 | 0.0035 |
Urine PH | 1213(96.1) | 5.9 ± 0.7 | 6.0 ± 0.7 | 0.48 |
HbA1c, % | 1043(82.6) | 6.3 ± 1.1 | 6.5 ± 1.2 | 0.006 |
Hs-CRP, mmol/l | 849(67.3) | 3.8 ± 5.7 | 6.6 ± 13.0 | < 0.001 |
Uric acid, mmol/l | 994(78.8) | 364.6 ± 92.7 | 389.3 ± 102.5 | < 0.001 |
B-type natriuretic peptide, pg/m | 1041(82.5) | 609.4 ± 2061.0 | 772.4 ± 2289.0 | 0.29 |