Analysis of cardiovascular mortality, bleeding, vascular and cerebrovascular events in patients with atrial fibrillation vs. sinus rhythm undergoing transfemoral Transcatheter Aortic Valve Implantation (TAVR)

Table 5 Life-threatening bleeding

Follow-up	Total population (n = 257)	SR-group(n = 148)	AF-group(n = 109)	p Value	OR (95% CI)
30 days	7.4% (19/257)	4.1% (6/148)	11.9% (13/109)	0.028	3.21 (1.18–8.72)
3 months	7.8% (20/257)	4.7% (7/148)	11.9% (13/109)	0.057	2.73 (1.05–7.09)
6 months	8.2% (20/241)	5.0% (7/137)	12.5% (13/104)	0.057	2.69 (1.04–7.01)
12 months	9.0% (20/219)	5.6% (7/124)	13.5% (13/95)	0.057	2.66 (1.02–6.96)

Shows the life-threatening bleeding events of all patients and of the two groups during the course of the follow-up period. The parentheses list the number of life-threatening bleeding events and the number of patients available for analysis
Patients with AF showed nearly three times more life-threatening bleeding events than patients with SR. This result corresponds to the rates and the temporal development of major vascular complications. Most of the life-threatening bleeding occurred peri-precidually and during initiation of oral anticoagulation or dual anti-platelet therapy. Thereafter, no significant differences were determined

ISSN: 1471-2261