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Table 3 Partial correlation after adjustment for model 1–3

From: Retinal capillary rarefaction in patients with untreated mild-moderate hypertension

Adjustment for model 1

 

Total study population

Hypertensive patients

Healthy control subjects

 ICD (μm) and WLR (−)

r = 0.146

r = 0.192

r = −0.150

p = 0.060

p = 0.035

p = 0.343

 CapA (−) and WLR (−)

r = −0.195

r = −0.189

r = −0.128

p = 0.011

p = 0.038

p = 0.419

 ICD (μm) and HDL (mmol/L)

r = −0.187

r = −0.112

r = 0.010

p = 0.014

p = 0.278

p = 0.964

 CapA (−) and HDL (mmol/L)

r = 0.156

r = 0.069

r = 0.027

p = 0.040

p = 0.502

p = 0.902

Adjustment for model 2

 

Total study population

Hypertensive patients

Healthy control subjects

 ICD (μm) and WLR (−)

r = 0.192

r = 0.254

r = 0.027

p = 0.014

p = 0.006

p = 0.873

 CapA (−) and WLR (−)

r = −0.229

r = −0.276

r = −0.175

p = 0.003

p = 0.003

p = 0.293

 ICD (μm) and HDL (mmol/L)

r = −0.172

r = −0.083

r = −0.032

p = 0.025

p = 0.428

p = 0.889

 CapA (−) and HDL (mmol/L)

r = 0.148

r = 0.026

r = 0.098

p = 0.050

p = 0.803

p = 0.672

 ICD (μm) and systolic 24ABP

r = 0.253

  

p = 0.009

  

 ICD (μm) and diastolic 24ABP

r = 0.190

  

p = 0.050

  

 ICD (μm) and systolic OBP

r = 0.143

  

p = 0.060

  

Adjustment for model 3

 ICD (μm) and WLR (−)

r = 0.227

r = 0.231

r = 0.133

p = 0.018

p = 0.032

p = 0.611

 CapA (−) and WLR (−)

r = −0.256

r = −0.212

r = −0.431

p = 0.007

p = 0.048

p = 0.084

 ICD (μm) and HDL (mmol/L)

r = −0.243

r = −0.210

r = −0.252

p = 0.011

p = 0.051

p = 0.329

 CapA (−) and HDL (mmol/L)

r = 0.224

r = 0.148

r = 0.387

p = 0.020

p = 0.172

p = 0.125

  1. ICD intercapillary distance, CapA capillary area, WLR wall to lumen ratio, HDL high density lipids, ABP ambulatory blood pressure, OBP office blood pressure.
  2. The data for the healthy control subjects have been previously described by our study group [21]
  3. Model 1 includes: gender, BMI, systolic office BP, serum-creatinine and HDL-cholesterol
  4. Model 2 includes: gender, BMI, systolic office BP, serum-creatinine and HDL-cholesterol, age, LDL- cholesterol and ex-smoking habit
  5. Model 3 includes: gender, BMI, serum creatinine, HDL-cholesterol, systolic 24 h ambulatory BP