Table 1 Baseline characteristics of the participants as randomised, and as included in the primary analysis
From: Unloading shoes for intermittent claudication: a randomised crossover trial
Characteristic | As randomised | As analysed | ||||
|---|---|---|---|---|---|---|
AB (n = 18) | BA (n = 19) | Total (n = 37) | AB (n = 15) | BA (n = 19) | Total (n = 34) | |
Age, years, mean (SD) | 67.3 (14.9) | 66.5 (10.2) | 66.9 (12.5) | 70.6 (8.8) | 66.5 (10.2) | 68.3 (9.7) |
Gender, male | 12 (67) | 15 (79) | 27 (73) | 12 (80) | 15 (79) | 27 (79) |
Ethnic origin, White British | 18 (100) | 19 (100) | 37 (100) | 15 (100) | 19 (100) | 34 (100) |
Ankle-brachial index, mean (SD) | 0.52 (0.13) | 0.54 (0.16) | 0.53 (0.14) | 0.53 (0.13) | 0.54 (0.16) | 0.54 (0.14) |
Duration of claudication symptoms, months, median (range) | 15 (6, 125) | 30 (4, 249) | 16 (4, 249) | 15 (6, 125) | 30 (4, 249) | 18 (4, 249) |
Body mass index, kg/m2, mean (SD) | 27.8 (4.2) | 28.4 (4.8) | 28.1 (4.5) | 28.8 (3.8) | 28.4 (4.8) | 28.5 (4.4) |
Heart rate, beats/min, mean (SD) | 73 (12) | 72 (11) | 72 (11) | 75 (12) | 72 (11) | 73 (11) |
Systolic blood pressure, mmHg, mean (SD) | 158 (21) | 143 (25) | 150 (24) | 156 (22) | 143 (25) | 149 (24) |
Diastolic blood pressure, mmHg, mean (SD) | 83 (12) | 81 (10) | 82 (11) | 84 (13) | 81 (10) | 82 (11) |
Current smoker | 4 (22) | 2 (10) | 6 (16) | 4 (27) | 2 (10) | 6 (18) |
Previous smoker | 12 (67) | 14 (74) | 26 (70) | 11 (73) | 14 (74) | 25 (73) |
Never smoked | 2 (11) | 3 (16) | 5 (14) | 0 (0) | 3 (16) | 3 (9) |
Diabetes mellitus | 4 (22) | 5 (26) | 9 (24) | 4 (27) | 5 (26) | 9 (27) |
Hypertension | 14 (78) | 13 (68) | 27 (73) | 12 (80) | 13 (68) | 25 (74) |
Hyperlipidaemia | 14 (78) | 14 (74) | 28 (76) | 13 (87) | 14 (74) | 27 (79) |
Chronic obstructive pulmonary disease | 1 (6) | 2 (11) | 3 (8) | 0 (0) | 2 (11) | 2 (6) |
Arthritis | 2 (11) | 2 (11) | 4 (11) | 1 (7) | 2 (11) | 3 (9) |
History of angina | 2 (11) | 6 (32) | 8 (22) | 2 (13) | 6 (32) | 8 (24) |
History of myocardial infarction | 0 (0) | 6 (32) | 6 (16) | 0 (0) | 6 (32) | 6 (18) |
History of stroke/transient ischaemic attack | 3 (17) | 2 (11) | 5 (14) | 3 (20) | 2 (11) | 5 (15) |
Anti-platelet/Anti-coagulant medication | 13 (72) | 14 (74) | 27 (73) | 12 (80) | 14 (74) | 26 (77) |
Lipid-lowering medication | 14 (78) | 13 (68) | 27 (73) | 13 (87) | 13 (68) | 26 (77) |
Anti-diabetic medication | 3 (17) | 4 (21) | 7 (19) | 3 (20) | 4 (21) | 7 (21) |
Beta-blockers | 3 (17) | 4 (21) | 7 (19) | 1 (7) | 4 (21) | 5 (15) |
Other anti-hypertensive medication | 13 (72) | 14 (74) | 27 (73) | 11 (73) | 14 (74) | 25 (74) |
6-min walk distance, metres, mean (SD) | 372 (92) | 367 (106) | 369 (98) | 382 (95) | 367 (106) | 373 (100) |