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Table 2 Coefficient of the function of heart in rats in every group 6 h following CME modeling: the echocardiologic measurement conclusions

From: The protective effect of activating Nrf2 / HO-1 signaling pathway on cardiomyocyte apoptosis after coronary microembolization in rats

Groups

LVEF (%)

FS (%)

LVEDd (mm)

CO (L/min)

Sham

89.25 ± 2.52

42.33 ± 2.56

5.67 ± 2.12

0.232 ± 0.018

CME

52.63 ± 1.78a

36.25 ± 3.22a

6.51 ± 3.33a

0.192 ± 0.033a

AAV-Nrf2 (CME)

70.44 ± 3.21ab

44.74 ± 1.58ab

5.79 ± 1.66ab

0.255 ± 0.025ab

AAV-control (CME)

52.87 ± 2.12a

34.55 ± 2.24a

6.48 ± 1.85a

0.201 ± 0.011a

  1. Data is shown as Mean ± SD
  2. AAV-Nrf2(CME) rats injected Nrf2 undergone CME operation, AAV-control (CME) rats injected AAV-control undergone CME operation, CME coronary microembolization, LVEF left ventricular ejection fraction, FS fractional shortening, LVEDd left ventricular end -diastolic diameter, CO cardiac output, Nrf2 nuclear factor erythroid 2-like, AAV adeno-associated virus
  3. a P < 0.05 contrasted with sham
  4. b P < 0.05 contrasted with CME or AAV control (CME)