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Table 4 Derived-vectorcardiographic angles and their respective sensitivities, specificities, positive and negative predictive values (PPV, NPV, respectively) and odds ratios (95% confidence intervals) for optimal cut-off values based on ROC curve analysis for the corrected QT interval (QTc), spatial peaks QRS-T angle (SPQRS-T angle), the right precordial directed angle (RPD angle angle), right root mean square QRS (RtRMS-QRS), and for both right parameters (RPD angle angle and RtRMS-QRS) at the above cut-off values) for ECG-negative ARVD/C versus controls

From: Right precordial-directed electrocardiographical markers identify arrhythmogenic right ventricular cardiomyopathy in the absence of conventional depolarization or repolarization abnormalities

Parameter

Optimum cut-off

AUC

p-value

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Odds ratio

QRSd

99.0 ms

0.64

0.026

48.5

83.3

74.4

61.8

4.7 (2.1 to 10.6)

QTc

451.0 ms

0.56

0.289

12.1

100.0

100.0

53.2

19.3 (1.1 to 342.1)

SPQRS-T angle

50.8°

0.68

<0.001

30.0

94.0

53.6

50.9

1.2 (0.5 to 2.7)

RPD angle

70.2°

0.86

<0.001

72.7

94.0

91.7

80.5

41.3 (13.1 to 130.2)

RtRMS-QRS

0.81 mV

0.85

<0.001

51.5

92.4

92.3

77.5

13.0 (4.6 to 36.4)

Both right parameters

N/A

N/A

N/A

81.8

90.9

90.0

83.3

45.0 (15.8 to 128.2)