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Table 4 Derived-vectorcardiographic angles and their respective sensitivities, specificities, positive and negative predictive values (PPV, NPV, respectively) and odds ratios (95% confidence intervals) for optimal cut-off values based on ROC curve analysis for the corrected QT interval (QTc), spatial peaks QRS-T angle (SPQRS-T angle), the right precordial directed angle (RPD angle angle), right root mean square QRS (RtRMS-QRS), and for both right parameters (RPD angle angle and RtRMS-QRS) at the above cut-off values) for ECG-negative ARVD/C versus controls

From: Right precordial-directed electrocardiographical markers identify arrhythmogenic right ventricular cardiomyopathy in the absence of conventional depolarization or repolarization abnormalities

Parameter Optimum cut-off AUC p-value Sensitivity (%) Specificity (%) PPV (%) NPV (%) Odds ratio
QRSd 99.0 ms 0.64 0.026 48.5 83.3 74.4 61.8 4.7 (2.1 to 10.6)
QTc 451.0 ms 0.56 0.289 12.1 100.0 100.0 53.2 19.3 (1.1 to 342.1)
SPQRS-T angle 50.8° 0.68 <0.001 30.0 94.0 53.6 50.9 1.2 (0.5 to 2.7)
RPD angle 70.2° 0.86 <0.001 72.7 94.0 91.7 80.5 41.3 (13.1 to 130.2)
RtRMS-QRS 0.81 mV 0.85 <0.001 51.5 92.4 92.3 77.5 13.0 (4.6 to 36.4)
Both right parameters N/A N/A N/A 81.8 90.9 90.0 83.3 45.0 (15.8 to 128.2)