Skip to main content

Table 1 Baseline clinical characteristics and biochemical assessments

From: Association of the single nucleotide polymorphism in chromosome 9p21 and chromosome 9q33 with coronary artery disease in Chinese population

 

CAD (n = 555)

Control (n = 480)

p-value

Male

62.52

50.21

<0.001

Age, yrs

62.94 ± 9.68

61.97 ± 9.83

0.11

Smoking

43.96

20.42

<0.001

BMI, kg/m2

24.37 ± 3.14

25.63 ± 3.14

0.034

Hypertension

78.37

78.65

0.923

Diabetes mellitus

67.39

31.25

<0.001

Hyperlipidemia

18

13.7

0.101

Family history

6.3

3.8

0.063

SBP, mmHg

133 ± 20

134 ± 19

0.387

DBP, mmHg

79 ± 12

81 ± 11

0.008

Total cholesterol, mmol/L

4.53 ± 1.10

4.67 ± 0.99

0.031

Triglyceride, mmol/L

1.93 ± 1.48

1.79 ± 1.23

0.096

HDL, mmol/L

1.11 ± 0.29

1.26 ± 0.30

<0.001

LDL-C, mmol/L

2.68 ± 0.92

2.69 ± 0.76

0.943

ApoA, g/L

1.20 ± 0.19

1.28 ± 0.20

<0.001

ApoB, g/L

0.91 ± 0.25

0.88 ± 0.22

0.054

LPA, g/L

0.28 ± 0.49

0.24 ± 0.49

0.286

Fasting glucose, mmol/L

6.81 ± 2.49

5.60 ± 1.66

<0.001

Creatinine, mg/L

88.94 ± 35.15

80.04 ± 22.53

<0.001

BUN, mmol/L

5.95 ± 2.87

5.58 ± 1.78

0.019

Uric acid, umol/L

318.90 ± 88.95

314.39 ± 79.32

0.415

HWE (rs7025486)

P = 0.840

P = 0.861

 

HWE (rs1333049)

P = 0.237

P = 0.306

 
  1. Values are mean ± SD or n (%)
  2. BMI Body mass index, BUN Blood urine nitrogen, CAD Coronary artery disease, HDL High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, LPA Lipoprotein A, HWE Hardy-Weinberg equilibrium
  3. P-values of risk factors with significance are presented as italic form