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Table 4 Predictors of mortality to all causes of heart failure

From: Anemia in severe heart failure patients: does it predict prognosis?

Variables

 

Univariate analysis

Multivariate analysis

 
  

Hazard ratio (95% CI)

Hazard ratio (95% CI)

P- value

Gender

Female

1.122 (0.643–1.958)

–

 

Age, Years

 

1.039 (1.021–1.058)

1.041 (1.017–1.066)

0.001*

NYHA Class

Class IV

1.622 (0.764–3.442)

0.946 (0.402–2.227)

0.899

Heart Rate, bpm

 

1.005 (0.992–1.017)

–

 

Systolic BP, mmHg

 

1.017 (1.008–1.026)

0.992 (0.975–1.009)

0.367

Diastolic BP, mmHg

 

1.031 (1.016–1.046)

1.020 (0.997–1.044)

0.089

Anemia

 

1.740 (1.004–3.016)

0.862 (0.439–1.693)

0.666

Sodium, mEq/L

 

0.937 (0.903–0.973)

0.933 (0.882–0.987)

0.016*

Creatinine, mg/dl

 

1.877 (1.636–2.155)

1.869 (1.460–2.392)

<0.0001*

AF

Yes

0.535 (0.275–1.039)

1.913 (0.583–6.272)

0.284

VHD

Yes

0.635 (0.366–1.103)

0.821 (0.418–1.612)

0.566

IHD

Yes

2.261 (1.228–4.162)

0.620 (0.256–1.501)

0.289

HHD

Yes

0.918 (0.449–1.876)

–

 

DCMP

Yes

0.878 (0.346–2.227)

–

 

Cor pulmonare

Yes

0.776 (0.106–5.691)

–

 

Other etiology

Yes

1.237 (0.443–3.453)

–

 

LVEF, %

 

0.977 (0.955–0.998)

0.984 (0.955–1.014)

0.283

Diuretics

Yes

0.586 (0.229–1.496)

–

 

Spironolactone

Yes

0.359 (0.210–0.613)

0.527 (0.276–0.996)

0.050*

ACEI

Yes

0.546 (0.311–0.960)

0.410 (0.197–0.852)

0.017*

Beta Blocker

Yes

0.555 (0.320–0.964)

0.578 (0.295–1.132)

0.110

Digoxin

Yes

0.401 (0.201–0.800)

0.634 (0.225–1.791)

0.390

Antiplatelates

Yes

0.895 (0.478–1.674)

–

 

Anticoagulants

Yes

0.400 (0.180–0.888)

0.841 (0.277–2.558)

0.760

Statin

Yes

1.431 (0.754–2.715)

–

 

CCB

Yes

1.524 (0744–3.119)

–

 
  1. ACEI Angiotensin converting enzyme inhibitor, AF Atrial Fibrillation, BP blood pressure, CCB calcium channel blocker, DCMP Dilated Cardiomyopathy, HHD hypertensive heart disease, IHD Ischemic heart disease, LVEF Left ventricular ejection fraction, NYHA New York Heart Association
  2. *p < 0.05