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Table 2 New-Onset Cardiovascular (CV) Events Stratified by Baseline PR Interval and QRS Duration

From: PR interval prolongation in coronary patients or risk equivalent: excess risk of ischemic stroke and vascular pathophysiological insights

(a). PR interval

New-Onset CV Events n (%)

Total (n = 597)

PR Interval < 200 ms (n = 518)

PR Interval > 200 ms (n = 79)

P-value

ROC C-Statistic

Estimate

P-value

Myocardial infarction

26 (4%)

20 (4%)

6 (8%)

0.130

0.70

0.001*

Ischemic stroke

21 (4%)

14 (3%)

7 (9%)

0.006*

0.50

0.99

Congestive heart failure

37 (6%)

28 (5%)

9 (11%)

0.040*

0.60

0.042*

CV death

27 (5%)

17 (3%)

10 (13%)

<0.001*

0.63

0.020*

Combined CV endpoints

87 (19%)

65 (13%)

22 (28%)

<0.001*

0.61

0.001*

(b). QRS duration

New-Onset CV Events n (%)

 

QRS Duration <120 ms (n = 556)

QRS Duration >120 ms (n = 36)

P-value

ROC C-Statistic

Estimate

P-value

Myocardial infarction

-

22 (4%)

3 (8%)

0.21

0.55

0.37

Ischemic stroke

-

20 (4%)

1 (3%)

0.80

0.47

0.60

Congestive heart failure

-

30 (5%)

7 (19%)

0.001*

0.59

0.08

CV death

-

24 (4%)

3 (8%)

0.26

0.62

0.03*

Combined CV endpoints

-

76 (14%)

10 (28%)

0.020*

0.56

0.08

  1. *P<0.05