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Table 1 Baseline characteristics of Participants by PR Interval Status (n = 597)a

From: PR interval prolongation in coronary patients or risk equivalent: excess risk of ischemic stroke and vascular pathophysiological insights

 

PR Interval ≤ 200 ms (n = 518)

PR Interval > 200 ms (n = 79)

p-value

Male [n (%)]

334 (65%)

67 (85%)

<0.001*

Age (years)

65.0 ± 11.1

70.5 ± 9.6

<0.001*

Body mass index (kgm−2)

25.2 ± 3.5

25.6 ± 3.2

0.34

Coronary Artery Disease [n (%)]

276 (53%)

52 (66%)

0.037*

Prior stroke [n (%)]

105 (21%)

26 (33%)

0.017*

Diabetes mellitus [n (%)]

274 (53%)

36 (46%)

0.23

Hypertension [n (%)]

330 (65%)

57 (72%)

0.20

Hyperlipidemia [n (%)]

320 (64%)

47 (60%)

0.48

Current/Past smoker [n (%)]

211 (42%)

43 (54%)

0.042

Regular Physical activity [n (%)]

185 (37%)

25 (12%)

0.40

Resting pulse rate (/min)

60.3 ± 21.2

63.7 ± 15.4

0.18

Systolic blood pressure (mmHg)

141.1 ± 20.5

140.2 ± 18.6

0.71

Diastolic blood pressure (mmHg)

79.0 ± 9.6

78.7 ± 9.3

0.83

LDL-cholesterol (mmol/L)

2.7 ± 0.7

2.4 ± 0.70

0.001*

HDL-cholesterol (mmol/L)

1.3 ± 0.3

1.2 ± 0.4

0.14

Tiglycerides (mmol/L)

1.5 ± 1.0

1.4 ± 0.7

0.37

Fasting glucose (mmol/L)

6.3 ± 2.1

6.1 ± 1.9

0.32

HbA1c (%)

7.0 ± 1.5

6.8 ± 1.2

0.22

hs-CRP (mg/L)

3.0 ± 8.9

2.7 ± 5.7

0.80

Serum creatinine (μmol/L)

86.9 ± 29.2

106.9 ± 59.6

0.005*

Medications:

 ACEI/ARB [n (%)]

268 (54%)

55 (70%)

0.008*

 Beta-blockers [n (%)]

241 (49%)

43 (54%)

0.39

 Calcium channel blockers [n (%)]

140 (28%)

22 (28%)

0.97

 Aspirin [n (%)]

323 (65%)

62 (79%)

0.017*

 Statin [n (%)]

285 (57%)

49 (62%)

0.41

PR interval (ms)

164.7 ± 19.0

222.6 ± 22.0

<0.001*

QRS duration (ms)

94.3 ± 27.1

99.0 ± 17.8

0.14

Mean Carotid IMT (mm)

0.94 ± 0.28

1.05 ± 0.37

0.010*

  1. HDL high-density lipoprotein, LDL low-density lipoprotein, HbA1c glycosylated haemoglobin A1c, hs-CRP high-sensitivity C-reactive protein, ACEI angiotensin-converting enzyme inhibitors, ARB angiotensin receptor blockers, IMT intima-media thickness
  2. *P-value < 0.05
  3. aAll values are \( \overline{x} \) ± SD, except where indicated otherwise