Prognostic value of short-term follow-up BNP in hospitalized patients with heart failure

Table 3 Area under curve (AUC), net reclassification improvement (NRI) and integrated discrimination improvement (IDI).for specific models using the 240 Patients with BNP at admission, after discharge and (%) changes of BNP

BNP		death
BNP		value	p-value
Initial BNP	AUC (95% CI)
	Traditional model	0.782 (0.722 ~ 0.842)	-
	Traditional model + BNP at admission	0.783 (0.724 ~ 0.843)	0.4683
	NRI (95% CI)	0.014 (−0.25 ~ 0.278)	0.9183
	IDI (95% CI)	0.00013 (−0.002 ~ 0.002)	0.8909
Follow up BNP	AUC (95% CI)
	Traditional model	0.782 (0.722 ~ 0.842)	-
	Traditional model + BNP at discharge	0.828 (0.777 ~ 0.879)	0.0205
	NRI (95% CI)	0.707 (0.465 ~ 0.949)	<.0001
	IDI (95% CI)	0.072 (0.037 ~ 0.106)	<.0001
(%) Changes of BNP	AUC (95% CI)
	Traditional model	0.782 (0.722 ~ 0.842)	-
	Traditional model + BNP change	0.852 (0.805 ~ 0.899)	0.0023
	NRI (95% CI)	0.782 (0.544 ~ 1.021)	<.0001
	IDI (95% CI)	0.113 (0.071 ~ 0.155)	<.0001

Traditional model: Age, sex, diabetes mellitus, hypertension, ischemic heart disease, chronic obstructive pulmonary disease, chronic kidney disease, stroke, sodium (Na), creatinine (Cr), hemoglobin (Hb) and EF

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