Common PIMs | Number | Percent |
---|---|---|
Drugs that may exacerbate or cause SIADH or hyponatremia (including diuretics, SSRIs, SNRIs, and antipsychotics) | 283 | 29.7 |
Scheduled use of PPIs >8 weeks in non-high risk patients | 108 | 11.3 |
Benzodiazepines | 77 | 8.1 |
Cardiovascular agents that should be avoided or dose reduced due to varying levels of kidney function (including NOACs and potassium sparing diuretics) | 66 | 6.9 |
CNS and analgesic agents that should be avoided or dose reduced due to varying levels of kidney function (including duloxetine, gabapentin, pregabalin, and tramadol) | 53 | 5.6 |
Combination of opioid analgesics with ≥2 other CNS active agents | 39 | 4.1 |
Anticholinergics | 38 | 4.0 |
H2 antagonists that should be dose reduced due to varying levels of kidney function | 29 | 3.0 |
Digoxin used as first line therapy for atrial fibrillation / flutter or heart failure or dose >0.125 mg/d | 23 | 2.4 |
Chronic use of non-cyclooxygenase-selective NSAIDS | 23 | 2.4 |
Skeletal muscle relaxants | 23 | 2.4 |