Statin use reduces cardiovascular events and all-cause mortality amongst Chinese patients with type 2 diabetes mellitus: a 5-year cohort study

Table 4 Multivariable Cox proportional hazard regression on the dependent variables of CVD event and all-cause mortality

	Statin Group Comparing with Comparison Group
	HR^a	95%CI	P-value
Main Analysis (N = 20,208)
CVD	0.458	(0.415,0.504)	<0.001*
CHD	0.436	(0.380,0.502)	<0.001*
Heart Failure	0.488	(0.402,0.593)	<0.001*
Stroke	0.429	(0.368,0.499)	<0.001*
All-cause Mortality	0.378	(0.331,0.431)	<0.001*
Sensitivity Analysis (N = 15,776)
CVD	0.522	(0.462,0.589)	<0.001*
CHD	0.467	(0.390,0.559)	<0.001*
Heart Failure	0.581	(0.454,0.742)	<0.001*
Stroke	0.516	(0.428,0.622)	<0.001*
All-cause Mortality	0.382	(0.325,0.450)	<0.001*

Sensitivity analysis: exclude subjects with follow-up period less than 2 years
CVD Cardiovascular Disease, CHD Coronary Heart Disease, HR Hazard Ratio, CI Confidence Interval
*p-value <0.05
^aHazard ratios were adjusted by age, gender, smoking status, haemoglobin A1c, systolic blood pressure, diastolic blood pressure, triglyceride, low density liporotein-cholesterol, body mass index, total cholesterol-to-high density lipoprotein-cholesterol ratio, presence of chronic kidney disease, duration of diabetes mellitus, Charlson Index, diagnosed hypertension, family history of diabetes mellitus and usages of insulin, oral and anti-hypertensive drugs index at baseline

ISSN: 1471-2261