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Table 1 Significant differences in clinical features among the four groups

From: Expression levels of atherosclerosis-associated miR-143 and miR-145 in the plasma of patients with hyperhomocysteinaemia

 

NC

Hhcy

Hhcy + ATH

ATH

P-value

Males/females

10/10

14/11

20/10

15/10

0.682

Age (years)

48.00 ± 4.44

47.16 ± 5.50

49.00 ± 5.47

46.92 ± 5.20

0.445

BMI (kg/m2)

24.13 ± 2.84

23.47 ± 2.30

25.03 ± 3.58

23.13 ± 2.68

0.080

TC (mmol/l)

3.94 ± 0.79

4.60 ± 0.99

5.56 ± 1.26

4.34 ± 1.04

<0.001**

TG (mmol/l)

1.12 ± 0.07

1.37 ± 0.04

1.45 ± 0.09

1.41 ± 0.11

0.001**

HDL-c (mmol/l)

1.43 ± 0.55

1.58 ± 0.63

1.59 ± 0.57

1.82 ± 0.66

0.176

LDL-c (mmol/l)

2.74 ± 0.91

3.46 ± 0.88

3.36 ± 0.93

3.18 ± 0.81

0.043*

ApoA(g/l)

1.32 ± 0.22

1.39 ± 0.27

1.39 ± 0.41

1.47 ± 0.31

0.480

ApoA/B

1.51 ± 0.42

1.57 ± 0.5

1.42 ± 0.45

1.53 ± 0.43

0.671

ApoB(g/l)

0.96 ± 0.25

0.93 ± 0.19

1.01 ± 0.28

1.01 ± 0.31

0.580

FBG (mmol/l)

5.06 ± 0.74

4.93 ± 0.55

5.07 ± 0.5

4.93 ± 0.59

0.722

ALT (U/l)

22.8 ± 13.02

19.8 ± 10.17

27.0 ± 12.8

20.48 ± 10.86

0.100

AST (U/l)

20.25 ± 10.17

20.84 ± 10.02

20.57 ± 12.36

21.2 ± 10.73

0.993

UA (umol/l)

255.65 ± 63.2

302.96 ± 105.9

258.9 ± 114.2

224.12 ± 106.1

0.795

Cre (umol/l)

73.68 ± 22.12

75.72 ± 24.12

71.3 ± 16.16

69.88 ± 19.84

0.754

Hcy (umol/l)

9.53 ± 2.99

19.07 ± 2.85

21.90 ± 4.69

11.16 ± 2.43

< 0.001**

  1. Continuous and categorical variables data were expressed as mean ± SEM. The statistical P value was generated by the one-way ANOVA test or Kruskal-Wallis test. χ2 test was employed to compare gender distribution. *P < 0.05 or **P < 0.001 was considered significant