| Unadjusted Hazard Ratio | p Value | Adjusted Hazard Ratio | p Value |
---|---|---|---|---|
Vascular | ||||
 Major | 0.46 (0.33–0.64) | <0.001 | 0.42 (0.37–0.49) | <0.001 |
 Minor | 0.79 (0.64–0.97) | 0.023 | 0.73 (0.58–0.93) | 0.011 |
Stroke | 0.31 (0.19–0.50) | <0.001 | 0.35 (0.22–0.55) | <0.001 |
MI | 0.33 (0.11–1.02) | 0.055 | 0.6 (0.42–0.84) | 0.003 |
Arrhythmia | 0.88 (0.76–1.02) | 0.090 | 0.75 (0.61–0.93) | 0.008 |
Permanent Pacemaker | 0.59 (0.48–0.73) | <0.001 | 0.49 (0.37–0.64) | <0.001 |
Bleeding | ||||
 Life Threatening | 0.30 (0.17–0.55) | <0.001 | 0.28 (0.17–0.46) | <0.001 |
 Major | 0.54 (0.38–0.76) | <0.001 | 0.56 (0.46–0.68) | <0.001 |
 Minor | 0.69 (0.49–0.98) | 0.036 | 0.82 (0.7–0.95) | 0.009 |
Transfusion | 0.56 (0.46–0.68) | <0.001 | 0.59 (0.54–0.65) | <0.001 |
Cardio-pulmonary bypass | 0.32 (0.12–0.87) | 0.025 | 0.27 (0.18–0.41) | <0.001 |
Emergency operation | 0.31 (0.15–0.65) | 0.002 | 0.31 (0.11–0.91) | 0.033 |
Open heart surgery | 0.29 (0.09–0.89) | 0.030 | 0.27 (0.18–0.41) | <0.001 |
Any Major Complicationa | 0.44 (0.37–0.52) | <0.001 | 0.38 (0.28–0.5) | <0.001 |