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Table 1 Study characteristic by cumulative social risk (3 categories)

From: Association of cumulative social risk with mortality and adverse cardiovascular disease outcomes

Traditional risk factors

Overall

N = 1731

CSR = 0

N = 607

CSR = 1

N = 520

CSR ≥2

N = 604

p-value

 Age (yrs)

59.1 (7.4)

59.7 (7.3)

59.2 (7.6)

58.3 (7.4)

0.004

 Male

593 (34.3%)

270 (44.5%)

185 (35.6%)

138 (22.9%)

<0.001

 Smoker

188 (10.9%)

43 (7.1%)

44 (8.5%)

101 (16.7%)

<0.001

 SBP (mmHg)

136.2(19.4)

133.1 (18.1)

134.9 (18.2)

140.9 (20.9)

<0.001

 DBP (mmHg)

80.7 (10.4)

79.0 (10.0)

80.4 (9.8)

82.6(10.9)

<0.001

 Diabetes

169 (9.8%)

31 (5.1%)

43 (8.3%)

95 (15.7%)

<0.001

 Hypertension

727 (42.0%)

190 (31.3%)

205 (39.4%)

332 (55.0%)

<0.001

 BMI (kg/m2)

30.0 (6.1)

28.3 (5.3)

29.8 (5.8)

31.7 (6.8)

<0.001

 TC (mg/dL)

213.2 (42.6)

214.3 (41.4)

213.6 (41.3)

211.9 (44.9)

0.613

 HDL-c (mg/dL)

57.6 (14.8)

56.8 (15.2)

57.1(14.2)

58.9 (14.9)

0.029

 TG (mg/dL)

122.6 (73.3)

130.8 (74.9)

122.6 (70.9)

114.3 (72.8)

<0.001

Components of CSR

 Race - Black

715 (41.3%)

0 (0.0%)

208 (40.0%)

507 (83.9%)

<0.001

 Low income

500 (28.9%)

0 (0.0%)

104 (20.0%)

396 (65.6%)

<0.001

 Single living

722 (41.7%)

0 (0.0%)

197 (37.9%)

525 (86.9%)

<0.001

  < High school

38 (2.2%)

0 (0.0%)

11 (2.1%)

27 (4.5%)

<0.001

Other variables

 Statin

361 (20.9%)

141 (23.2%)

108 (20.8%)

112 (18.6%)

0.14

 Family hx CAD

628 (36.3%)

194 (32.0%)

182 (35.0%)

252 (41.7%)

<0.001

 Depressiona

204 (11.8%)

39 (6.4%)

54 (10.4%)

111 (18.4%)

<0.001

 CESD score

6.86 (8.0)

5.29 (6.26)

6.50 (7.66)

8.74 (9.30)

<0.001

 Cohen score

4.26 (3.01)

3.71 (2.68)

4.28 (2.99)

4.78 (3.26)

<0.001

 DIS score

11.23 (6.2%)

9.58 (6.03)

11.43 (6.10)

12.73 (5.90)

<0.001

 Creatinine (mg/dl)

0.92 (0.27)

0.91 (0.18)

0.93 (0.33)

0.93 (0.29)

0.419

 HsCRP (mg/l)

2.91 (4.98)

2.34 (4.62)

2.64 (3.65)

3.73 (6.10)

<0.001

 IL6 (pg/ml)

2.21 (2.02)

1.78 (1.48)

2.20 (1.63)

2.66 (2.62)

<0.001

  1. CSR cumulative social risk score, Hx history, BP blood pressure, BMI body mass index, < High school – did not complete high school, TC total cholesterol, HDL-c high-density lipoprotein cholesterol, TG triglycerides, HsCRP high-sensitivity C-reactive protein, IL6 interleukin-6, CESD Center for Epidemiologic Studies Depression Scale, Cohen stress scale, DIS discrimination score. aDepression was defined as CES-D score ≥ 16. NB. The p-value is a test for statistical significant difference in the distribution of the respective variables across the categories of CSR. A p-value <0.05 is considered statistically significant