Table 2 Multiple COX regression model for the time-cumulated exposure to systolic blood pressure and to diastolic blood pressure in relation to the new-onset of impairment of glucose tolerance in 2563 (8.0%) individuals out of 31,935 participants without impairment of glucose tolerance and without diabetes at the baseline examinations
New-onset of impairment of glucose tolerance in participants without impairment of glucose tolerance and without diabetes at the baseline | Quartiles of cumulative systolic blood pressure (cumSBP) | Each increase in cumSBP by 10 mmHg·/ year | P-trend | |||
Q1 | Q2 | Q3 | Q4 | |||
cumSBP (Median) (mmHg x Year) | 439.1 | 498.6 | 538.4 | 614.1 | ||
Number of Participants (n) | 775 (5.8%) | 439 (7.5%) | 399 (8.8%) | 950 (11.8%) | <0.001 | |
Model 1 | 1.00 | 1.30 (1.15, 1.50) | 1.60 (1.41, 1.82) | 2.42 (2.17, 1.82) | 1.04 (1.03, 1.04) | <0.001 |
Model 2 | 1.00 | 1.29 (1.14, 1.45) | 1.56 (1.37, 1.78) | 2.32 (2.07, 2.60) | 1.03 (1.03, 1.04) | <0.001 |
Model 3 | 1.00 | 1.17 (1.02, 1.33) | 1.43 (1.25, 1.64) | 2.09 (1.85, 2.37) | 1.03 (1.03, 1.04) | <0.001 |
New-onset of impairment of glucose tolerance in participants without impairment of glucose tolerance and without diabetes at the baseline | Quartiles of cumulative diastolic blood pressure (cumDBP) | Each increase in cumDBP by 5 mmHg·/ year | P-trend | |||
Q1 | Q2 | Q3 | Q4 | |||
cumDBP (Median) (mmHg x Year) | 239.1 | 329.6 | 349.4 | 388.4 | ||
Number of Participants (n) | 875 (6.1%) | 391 (7.6%) | 388 (9.0%) | 909 (11.1%) | <0.001 | |
Model 1 | 1.00 | 1.26 (1.11, 1.42) | 1.55 (1.37, 1.75) | 2.35 (2.12, 2.60) | 1.03 (1.03, 1.03) | <0.001 |
Model 2 | 1.00 | 1.24 (1.10, 1.40) | 1.53 (1.35, 1.73) | 2.27 (2.05, 2.52) | 1.03 (1.02, 1.03) | <0.001 |
Model 3 | 1.00 | 1.12 (0.98, 1.27) | 1.35 (1.18, 1.54) | 2.02 (1.80, 2.25) | 1.02 (1.02, 1.03) | <0.001 |