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Table 5 Sensitivity analyses with inclusion of colchicine in the main model or with immune disease in the model

From: Allopurinol use and the risk of acute cardiovascular events in patients with gout and diabetes

 

Main modela + colchicine

Main modela + immune disease

 

Incident MI or stroke

 

Hazard ratio (95% CI)

p-value

Hazard ratio (95% CI)

p-value

Allopurinol User

 Current

0.68 (0.54, 0.85)

0.001

0.67 (0.53, 0.84)

0.0006

 Previous

Ref

 

Ref

 

Immune disease

--

--

1.04 (0.78, 1.37)

0.81

Colchicine

0.80 (0.55, 1.18)

0.26

--

--

  1. Significant odds ratios are in bold
  2. aMain model was run without immune disease and without colchicine and included gender, age, race, hypertension, hyperlipidemia, peripheral vascular disease COPD and renal disease