Table 4 Differences of HRV parameters (time-domain method) between type 1 diabetic patients with and without CAN

 R-R max / R-R min

1.12 ± 0.07

1.28 ± 0.18

<0.001

 SDNN (ms)

16.69 ± 8.50

45.16 ± 25.92

<0.001

 pNN50 (%)

0.95 ± 0.65

20.10 ± 2.56

<0.001

 CV (%)

2.27 ± 1.07

4.63 ± 2.38

<0.0001

 R-R max / R-R min

1.1 ± 0.05

1.36 ± 0.24

<0.001

 SDNN (ms)

31.87 ± 13.68

41.13 ± 16.24

0.02

 pNN50 (%)

1.60 ± 0.87

26.63 ± 2.38

<0.001

 CV (%)

2.09 ± 0.98

6.72 ± 4.27

<0.0001

 R-R max / R-R min

1.14 ± 0.18

1.38 ± 0.27

<0.001

 SDNN (ms)

24.85 ± 5.19

56.12 ± 4.44

<0.001

 pNN50 (%)

0.71 ± 0.50

12.18 ± 6.59

<0.001

 CV (%)

2.59 ± 1.65

6.37 ± 4.05

<0.0001