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Table 1 Clinical characteristics of young CHD patients from 2010 to 2014

From: Trend in young coronary artery disease in China from 2010 to 2014: a retrospective study of young patients ≤ 45

Variable

2010

(n = 804)

2011

(n = 930)

2012

(n = 1045)

2013

(n = 1241)

2014

(n = 1268)

P

Age

40.4 ± 4.2

40.6 ± 4.1

40.7 ± 4.2

40.8 ± 4.2

40.8 ± 4.2

NS

Male (%)

766 (91.2)

876 (94.2)

983 (94.1)

1146 (92.3)

1184 (93.4)

NS

SBP (mmHg)

123.9 ± 16.9

124.8 ± 16.9

123.9 ± 14.9

123.7 ± 15.3

123.5 ± 15.5

NS

DBP (mmHg)

78.2 ± 12.4

77.9 ± 12.1

77.0 ± 11.2

77.9 ± 11.4

77.6 ± 11.9

NS

HR

72.8 ± 11.8

72.4 ± 11.7

72.1 ± 11.2

74.3 ± 12.7

72.0 ± 11.0

0.000

BMI

27.9 ± 3.1

27.9 ± 3.2

27.7 ± 3.2

28.1 ± 3.1

27.6 ± 3.4

0.002

Risk factor

      

 Hypertension (%)

342 (40.7)

379 (40.7)

496 (47.5)

498 (40.1)

529 (41.7)

0.005

 Diabetes (%)

171 (20.3)

182 (19.6)

238 (22.7)

324 (26.1)

284 (22.4)

0.006

 Hyperlipidemia (%)

230 (27.3)

244 (26.2)

371 (35.5)

362 (29.1)

453 (35.7)

0.000

 Smoke (%)

502 (59.7)

572 (61.5)

646 (61.8)

710 (57.2)

728 (57.4)

0.020

 Alcohol use (%)

210 (25.0)

255 (27.4)

325 (31.1)

323 (26.0)

317 (25.0)

0.014

Geographical differences

      

 City area (%)

543 (67.5)

605 (65.1)

651 (65.2)

857 (69.1)

843 (66.5)

NS

Scholarship

     

0.000

 High (%)

436 (51.9)

466 (50.1)

594 (56.8)

735 (59.2)

744 (58.7)

 

 Middle (%)

269 (32.0)

369 (39.7)

331 (31.7)

376 (30.3)

384 (30.3)

 

 Low (%)

99 (11.8)

95 (10.2)

120 (11.5)

130 (10.5)

140 (11.0)

 

Diagnosis

     

0.000

 SA

24 (2.8)

21 (2.2)

18 (1.7)

27 (2.1)

13 (1.0)

0.024

 UA

394 (46.9)

505 (54.3)

566 (54.1)

706 (56.8)

723 (57.0)

0.003

 NSTEMI

325 (38.7)

350 (37.6)

340 (32.5)

389 (31.3)

364 (28.7)

0.000

 STEMI

52 (6.2)

41 (4.4)

104 (9.9)

99 (7.9)

151 (11.9)

0.000

 ICM

9 (1.1)

13 (1.4)

17 (1.6)

20 (1.6)

17 (1.3)

NS

Proportion of young CAD the total hospitalized patients (%)

5.4

5.8

5.7

6.9

7.2

0.000

Proportion of young CAD in the total Cardiac clinic (%)

2147 (1.2)

2085 (1.1)

2283 (1.2)

3279 (1.5)

3732 (1.7)

0.000

  1. Abbreviations: SBP systolic blood pressure, DBP diastolic blood pressure, HR heart rate, BMI body mass index, SA stable angina, UA unstable angina, NSTEMI non-ST-segment myocardial infarction, STEMI ST-segment elevation myocardial infarction, ICM ischemic cardiomyopathy, NS not significant