Variables | Without OSA | Mild | Moderate-severe | P value |
---|---|---|---|---|
N (%) | 286 (29.5) | 318 (32.7) | 367 (37.8) | |
Age (years) | 56.5 ± 13.3 | 59.9 ± 11.4 | 58.8 ± 11.9 | 0.002 |
Male (%) | 71.7 | 73.6 | 82.6 | <0.001 |
BMI (Kg/m2) | 24.6 ± 3.6 | 24.8 ± 3.4 | 26.6 ± 4.4 | <0.001 |
SBP (mm Hg) | 137.3 ± 20.4 | 137.7 ± 21.5 | 137.1 ± 21.5 | 0.934 |
DBP (mm Hg) | 79.3 ± 13.6 | 79.3 ± 14.8 | 79.4 ± 14.0 | 0.985 |
AHI | 1.7 ± 1.4 | 9.2 ± 2.7 | 33.1 ± 15.7 | <0.001 |
IVS (mm) | 10.7 ± 1.8 | 11.2 ± 2.6 | 11.5 ± 2.1 | <0.001 |
LVPW (mm) | 10.2 ± 1.8 | 10.3 ± 1.7 | 10.7 ± 1.9 | 0.001 |
HbA1c (%) | 6.1 ± 1.1 | 6.2 ± 1.1 | 6.2 ± 1.2 | 0.838 |
Creatinine (μmol/L) | 91.6 ± 48.0 | 92.7 ± 45.3 | 104.5 ± 79.2 | 0.012 |
BUN (mmol/L) | 5.5 ± 3.2 | 5.7 ± 2.9 | 5.9 ± 2.8 | 0.290 |
FPG (mmol/L) | 6.2 ± 2.6 | 6.3 ± 2.5 | 6.6 ± 3.4 | 0.097 |
Triglyceride (mmol/L) | 1.9 ± 0.3 | 1.7 ± 0.1 | 1.9 ± 0.1 | 0.665 |
Total cholesterol (mmol/L) | 4.5 ± 1.3 | 4.5 ± 1.3 | 4.6 ± 1.2 | 0.442 |
LDL-C (mmol/L) | 2.7 ± 1.0 | 2.7 ± 1.0 | 2.7 ± 1.0 | 0.938 |
HDL-C (mmol/L) | 1.0 ± 0.3 | 1.0 ± 0.2 | 1.0 ± 0.2 | 0.892 |
Proteinuria (%) | 17.1 | 18.5 | 22.0 | 0.027 |
Diabetes mellitus (%) | 19.6 | 23.0 | 25.6 | 0.038 |
Dyslipidemia (%) | 10.5 | 14.2 | 15.0 | 0.057 |
Aortic dissection (%) | 20.3 | 20.8 | 19.1 | 0.358 |
Aneurysm (%) | 4.5 | 4.7 | 6.0 | 0.221 |
CHD (%) | 37.4 | 39.9 | 43.6 | 0.058 |
Cerebrovascular disease (%) | 6.6 | 11.0 | 9.0 | 0.195 |
Heart failure (%) | 19.2 | 17.6 | 25.6 | 0.019 |
Atrial fibrillation (%) | 8.4 | 10.1 | 8.2 | 0.462 |
HCM (%) | 1.7 | 3.1 | 3.5 | 0.112 |
Anti-platelet (%) | 49.0 | 53.1 | 55.3 | 0.060 |
Statins (%) | 59.1 | 68.2 | 65.7 | 0.057 |
ACEI (%) | 22.0 | 22.0 | 22.1 | 0.514 |
ARB (%) | 49.7 | 45.3 | 46.6 | 0.249 |
Beta-blocker (%) | 59.4 | 62.9 | 69.5 | 0.004 |
Alpha-blocker (%) | 6.6 | 6.3 | 6.5 | 0.514 |
CCB (%) | 55.2 | 58.5 | 55.9 | 0.478 |
Diuretic (%) | 16.1 | 16.7 | 20.4 | 0.076 |
Warfarin (%) | 2.0 | 2.5 | 2.6 | 0.512 |