Trials | A | B | C | D | E | F | Total score | Bias grade |
---|
DEFER-DES | 2 | 2 | 2 | 2 | 1 | 1 | 10 | B |
DKCRUSH-VI | 2 | 2 | 2 | 1 | 2 | 1 | 10 | B |
FAME | 2 | 2 | 2 | 2 | 1 | 1 | 10 | B |
PLATFORM | 1 | 1 | 2 | 2 | 1 | 1 | 8 | C |
- A: Sequence generation
- B: Allocation sequence concealment
- C: Blinding of participants and personnel
- D: Blinding of outcome assessment
- E: Incomplete outcome data
- F: Selective outcome reporting and other potential bias