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Table 4 Associations between genotype and the Gensini score in the whole cohort and in patients without previous MI

From: The association of functional polymorphisms in genes encoding growth factors for endothelial cells and smooth muscle cells with the severity of coronary artery disease

  Genotype P value
Kruskal-Wallis
P value
Trend test
   C/C C/G G/G   
FGF2 Whole cohort 25 [16–48] 24 [14–59] 33.5 [22.8–45.5] 0.91 0.35*
Without previous MI 22 [15–44] 23.5 [14–56.8] 27 [20–34] 0.80 0.28*
   A/A A/G G/G   
EGF Whole cohort 24 [15–56.5] 26 [15.5–49.5] 22.3 [16–43.3] 0.79 0.34**
Without previous MI 22.5 [14–44] 25 [14–46] 20.5 [15.3–42.5] 0.68 0.34**
   A/A A/G G/G   
IGF1 Whole cohort 26 [20–44] 24.5 [14–44.3] 25 [16–56] 0.53 0.18*
Without previous MI 26.5 [21.9–44] 23 [12–43] 22 [14.5–46] 0.35 0.31*
   C/C T/C T/T   
PDGFB Whole cohort 22.8 [16–46] 25.5 [14–52] 25.5 [16–52.3] 0.78 0.25*
Without previous MI 22.3 [16.0–45.5] 22.5 [13–44.8] 22.0 [16.0–44] 0.75 0.32*
   A/A A/G G/G   
TGFB1 Whole cohort 24 [14–46] 25 [16–47] 26 [16–58] 0.5 0.14*
Without previous MI 24 [13.8–44.5] 22 [15.3–39.8] 22.5 [15.8–49.3] 0.96 0.45*
   A/A A/C C/C   
VEGFA Whole cohort 27 [17.5–46.3] 26 [16.0–56] 22 [14–47] 0.2 0.048**
Without previous MI 25 [17–44.5] 24.5 [14–46.4] 18 [12.0–43.3] 0.055 0.013**
  1. Jonckhere Terpstra test for trend: *increasing, **decreasing