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Table 4 Associations between genotype and the Gensini score in the whole cohort and in patients without previous MI

From: The association of functional polymorphisms in genes encoding growth factors for endothelial cells and smooth muscle cells with the severity of coronary artery disease

 

Genotype

P value

Kruskal-Wallis

P value

Trend test

  

C/C

C/G

G/G

  

FGF2

Whole cohort

25 [16–48]

24 [14–59]

33.5 [22.8–45.5]

0.91

0.35*

Without previous MI

22 [15–44]

23.5 [14–56.8]

27 [20–34]

0.80

0.28*

  

A/A

A/G

G/G

  

EGF

Whole cohort

24 [15–56.5]

26 [15.5–49.5]

22.3 [16–43.3]

0.79

0.34**

Without previous MI

22.5 [14–44]

25 [14–46]

20.5 [15.3–42.5]

0.68

0.34**

  

A/A

A/G

G/G

  

IGF1

Whole cohort

26 [20–44]

24.5 [14–44.3]

25 [16–56]

0.53

0.18*

Without previous MI

26.5 [21.9–44]

23 [12–43]

22 [14.5–46]

0.35

0.31*

  

C/C

T/C

T/T

  

PDGFB

Whole cohort

22.8 [16–46]

25.5 [14–52]

25.5 [16–52.3]

0.78

0.25*

Without previous MI

22.3 [16.0–45.5]

22.5 [13–44.8]

22.0 [16.0–44]

0.75

0.32*

  

A/A

A/G

G/G

  

TGFB1

Whole cohort

24 [14–46]

25 [16–47]

26 [16–58]

0.5

0.14*

Without previous MI

24 [13.8–44.5]

22 [15.3–39.8]

22.5 [15.8–49.3]

0.96

0.45*

  

A/A

A/C

C/C

  

VEGFA

Whole cohort

27 [17.5–46.3]

26 [16.0–56]

22 [14–47]

0.2

0.048**

Without previous MI

25 [17–44.5]

24.5 [14–46.4]

18 [12.0–43.3]

0.055

0.013**

  1. Jonckhere Terpstra test for trend: *increasing, **decreasing