Impact of impaired fractional flow reserve after coronary interventions on outcomes: a systematic review and meta-analysis

Table 2 Patient characteristics

	Bech et al.		Pijls et al.		Klauss et al.		Nam et al.		Leesar et al.		Ito et al.		Reith et al.		Doh et al.		Combined
FFR group	Low	High	Low	High	Low	High	Low	High	Low	High	Low	High	Low	High	Low	High	Low	High
N	32	26	237	507	53	66	40	40	31	35	53	44	26	40	20	95	492	853
Age (years) (SD)	61.5		62 (11)		62 (10)		62 (10)	63 (8)	63 (11)	60 (12)	71 (9)		69 (10)	69 (10)	64 (9)		65 (4)	64 (4)
Age (years) (SD)	61.5		62 (11)		62 (10)		62 (10)	63 (8)	63 (11)	60 (12)	71 (9)		69 (10)	69 (10)	64 (9)		64 (4)
Male (%)	69		NA		75		78	70	77	70	75		88	75	83		80	77
Male (%)	69		NA		75		78	70	77	70	75		88	75	83		77
HTN (%)	33		51		79		58	43	68	94	92		65	88	82		63	74
HTN (%)	33		51		79		58	43	68	94	92		65	88	82		61
Diabetes (%)	17		24		26		20	8	32	23	37		58	53	51		34	28
Diabetes (%)	17		24		26		20	8	32	23	37		58	53	51		28
HC (%)	31		61		83		10	15	58	74	85		54	60	68		37	49
HC (%)	31		61		83		10	15	58	74	85		54	60	68		61
Smoking (%)	24		48		38		28	48	32	46	54		15	23	30		26	38
Smoking (%)	24		48		38		28	48	32	46	54		15	23	30		41
FHx (%)	41		38		38		NA		NA		NA		39	63	NA		40
Prior MI (%)	17		NA		56		10	13	NA		NA		NA		5.6		25
MVD (%)	NA		NA		67		63	60	NA		NA		73	68	63		67	64
MVD (%)	NA		NA		67		63	60	NA		NA		73	68	63		65
LAD (%)	66		52		39		83	55	39	34	56		NA		100	71	71	59
LAD (%)	66		52		39		83	55	39	34	56		NA		100	71	54
Complex lesion^a (%)	NA		NA		65		90	78	NA		NA		NA		95	67	92	70
Complex lesion^a (%)	NA		NA		65		90	78	NA		NA		NA		95	67	72
FU (months)	24		6		6		12		24		18		20		23		16

Separate data provided for low FFR group and high FFR group if available from respective study, otherwise overall value
Abbreviations: FHx family history, FFR fractional flow reserve, FU follow up, HC hypercholesterolemia, HTN Hypertension, LAD left anterior descending artery, MI myocardial infarction, MVD multi-vessel-disease, N patient number, SD standard deviation
^aComplex lesion is defined as B2 or C category according to American College of Cardiology/American Heart Association (ACC/AHA) lesion classification

ISSN: 1471-2261