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Table 4 Evaluation of mean blood pressure at baseline and after therapy (PP analysis; N = 146)

From: Leg edema with (S)-amlodipine vs conventional amlodipine given in triple therapy for hypertension: a randomized double blind controlled clinical trial

Variable Test group Reference group p *
N mm of Hg (mean ± SD) N mm of Hg (mean ± SD)  
Baseline (day 0), V1 70 113.01 ± 25.93 76 113.99 ± 12.17 ns
After 30 days of therapy, V2 70 101.08 ± 17.92 76 95.33 ± 12.34 ns
After 60 days of therapy, V3 70 90.08 ± 06.01 76 89.81 ± 8.02 ns
After 90 days of therapy, V4 70 102.50 ± 14.34 76 99.01 ± 08.45 ns
After 120 days of therapy, V5 70 94.42 ± 17.25 76 95.89 ± 03.34 ns
p**   <0.0001   <0.0001  
  1. PP per protocol, N number of patients, SD standard deviation, ns not significant
  2. Paired t test was applied; *p value, when compared between the groups; **p value, when V5 value compared with baseline value in same group; p <0.05 = statistically significant