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Table 1 Baseline characteristics (for completed patients, N = 146)

From: Leg edema with (S)-amlodipine vs conventional amlodipine given in triple therapy for hypertension: a randomized double blind controlled clinical trial

Parameter

Test group

Reference group

p

Number of patients

70

76

na

Age in years; (mean ± SD)

56.46 ± 5.80

56.83 ± 5.57

ns

Weight; (kg) (mean ± SD)

63.82 ± 9.33

65.72 ± 11.94

ns

Male: Female

48:22

52:24

ns

Patients with type II diabetes; %, (n/N)

41.43, (29/70)

34.21, (26/76)

ns

Patients with history of angina; %, (n/N)

5.71, (4/70)

2.63, (2/76)

ns

Patients on captopril; %, (n/N)

32.85 % (23/70)

30.26 % (23/76)

ns

Patients on enalapril; %, (n/N)

31.42 % (22/70)

31.57 % (24/76)

ns

Patients on losartan;%, (n/N)

34.28 % (24/70)

38.15 % (29/76)

ns

Patients on atenolol; %, (n/N)

67.14 % (47/70)

63.15 % (48/76)

ns

Patients on carvedilol; %, (n/N)

14.28 % (10/70)

25 % (19/76)

ns

Patients on metoprolol;%, (n/N)

11.42 % (8/70)

7.89 % (6/76)

ns

Patients on bisoprolol; %, (n/N)

4.28 % (3/70)

2.63 % (2/76)

ns

Hb (mean ± SD)

13.61 ± 1.73

13.57 ± 1.55

ns

Total WBC count (mean ± SD)

7.67 ± 1.95

7.52 ± 1.91

ns

SGOT (mean ± SD)

32.94 ± 13.45

35.41 ± 19.20

ns

SGPT (mean ± SD)

35.86 ± 18.29

34.95 ± 20.79

ns

LDL (mean ± SD)

82.38 ± 26.83

77.26 ± 31.24

ns

HDL (mean ± SD)

40.24 ± 9.18

38.26 ± 8.19

ns

VLDL (mean ± SD)

29.29 ± 11.70

34.13 ± 22.02

ns

Total cholesterol (mean ± SD)

152.17 ± 33.59

150.28 ± 39.42

ns

Triglycerides (mean ± SD)

146.24 ± 58.34

158.25 ± 76.50

ns

Fasting blood glucose (mean ± SD)

116.57 ± 43.35

120.09 ± 52.84

ns

Serum creatinine (mean ± SD)

0.90 ± 0.31

0.87 ± 0.25

ns

  1. N total number of patients, n number of patients with the variable, SD standard deviation, na value not assessed, COPD chronic obstructive pulmonary disease, ns value not statistically significant with p > 0.05; Mann-Whitney test was applied for continuous variables and Fisher’s Exact test was applied for categorical variables