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Table 1 Baseline characteristics (for completed patients, N = 146)

From: Leg edema with (S)-amlodipine vs conventional amlodipine given in triple therapy for hypertension: a randomized double blind controlled clinical trial

Parameter Test group Reference group p
Number of patients 70 76 na
Age in years; (mean ± SD) 56.46 ± 5.80 56.83 ± 5.57 ns
Weight; (kg) (mean ± SD) 63.82 ± 9.33 65.72 ± 11.94 ns
Male: Female 48:22 52:24 ns
Patients with type II diabetes; %, (n/N) 41.43, (29/70) 34.21, (26/76) ns
Patients with history of angina; %, (n/N) 5.71, (4/70) 2.63, (2/76) ns
Patients on captopril; %, (n/N) 32.85 % (23/70) 30.26 % (23/76) ns
Patients on enalapril; %, (n/N) 31.42 % (22/70) 31.57 % (24/76) ns
Patients on losartan;%, (n/N) 34.28 % (24/70) 38.15 % (29/76) ns
Patients on atenolol; %, (n/N) 67.14 % (47/70) 63.15 % (48/76) ns
Patients on carvedilol; %, (n/N) 14.28 % (10/70) 25 % (19/76) ns
Patients on metoprolol;%, (n/N) 11.42 % (8/70) 7.89 % (6/76) ns
Patients on bisoprolol; %, (n/N) 4.28 % (3/70) 2.63 % (2/76) ns
Hb (mean ± SD) 13.61 ± 1.73 13.57 ± 1.55 ns
Total WBC count (mean ± SD) 7.67 ± 1.95 7.52 ± 1.91 ns
SGOT (mean ± SD) 32.94 ± 13.45 35.41 ± 19.20 ns
SGPT (mean ± SD) 35.86 ± 18.29 34.95 ± 20.79 ns
LDL (mean ± SD) 82.38 ± 26.83 77.26 ± 31.24 ns
HDL (mean ± SD) 40.24 ± 9.18 38.26 ± 8.19 ns
VLDL (mean ± SD) 29.29 ± 11.70 34.13 ± 22.02 ns
Total cholesterol (mean ± SD) 152.17 ± 33.59 150.28 ± 39.42 ns
Triglycerides (mean ± SD) 146.24 ± 58.34 158.25 ± 76.50 ns
Fasting blood glucose (mean ± SD) 116.57 ± 43.35 120.09 ± 52.84 ns
Serum creatinine (mean ± SD) 0.90 ± 0.31 0.87 ± 0.25 ns
  1. N total number of patients, n number of patients with the variable, SD standard deviation, na value not assessed, COPD chronic obstructive pulmonary disease, ns value not statistically significant with p > 0.05; Mann-Whitney test was applied for continuous variables and Fisher’s Exact test was applied for categorical variables