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Table 6 Differences in vascular changes in non-T2D subjects without or without treatment with any type of RAAS inhibitor

From: Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes

 

No T2D with CVD

No T2D without CVD

Variable

Yes

No

MedianYes

MedianNo

p-value

Yes

No

MedianYes

MedianNo

p-value

ABPI

146

76

1.16 (1.08–1.25)

1.13 (1.02–1.23)

ns

49

196

1.17 (1.12–1.23)

1.17 (1.10–1.25)

ns

CCA IMT (mm)

147

73

0.88 (0.78–1.04)

0.88 (0.78–0.99)

ns

48

192

0.92 (0.82–1.03)

0.81 (0.72–0.96)

7.4E-04

Bulb IMT (mm)

132

66

1.20 (0.98–1.44)

1.07 (0.96–1.31)

ns

47

187

1.15 (0.99–1.38)

0.96 (0.84–1.15)

1.9E-04

Plaque area (mm2)

128

67

18.5 (12.5–24.6)

13.58 (10.9–18.7)

0.004

40

134

15.8 (10.7–29.8)

13.2 (7.8–20.0)

ns

PWV (m/sec)

135

63

10.2 (8.3–11.8)

9.7 (8.5–11.8)

ns

46

189

9.8 (9.0–11.0)

9.2 (7.9–10.7)

0.025

RHI

158

77

2.2 (1.8–2.6)

2.3 (1.9–2.7)

ns

50

196

2.25 (1.88–2.48)

2.41 (2.00–2.81)

ns

  1. Difference of imaging marker was assessed by Mann-Whitney U-test, medians are presented together with IQRs
  2. ns not significant, ABPI ankle brachial pressure index, CCA common carotid artery, IMT intima media thickness, PWV pulse wave velocity, RHI reactive hyperemia index