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Table 6 Differences in vascular changes in non-T2D subjects without or without treatment with any type of RAAS inhibitor

From: Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes

  No T2D with CVD No T2D without CVD
Variable Yes No MedianYes MedianNo p-value Yes No MedianYes MedianNo p-value
ABPI 146 76 1.16 (1.08–1.25) 1.13 (1.02–1.23) ns 49 196 1.17 (1.12–1.23) 1.17 (1.10–1.25) ns
CCA IMT (mm) 147 73 0.88 (0.78–1.04) 0.88 (0.78–0.99) ns 48 192 0.92 (0.82–1.03) 0.81 (0.72–0.96) 7.4E-04
Bulb IMT (mm) 132 66 1.20 (0.98–1.44) 1.07 (0.96–1.31) ns 47 187 1.15 (0.99–1.38) 0.96 (0.84–1.15) 1.9E-04
Plaque area (mm2) 128 67 18.5 (12.5–24.6) 13.58 (10.9–18.7) 0.004 40 134 15.8 (10.7–29.8) 13.2 (7.8–20.0) ns
PWV (m/sec) 135 63 10.2 (8.3–11.8) 9.7 (8.5–11.8) ns 46 189 9.8 (9.0–11.0) 9.2 (7.9–10.7) 0.025
RHI 158 77 2.2 (1.8–2.6) 2.3 (1.9–2.7) ns 50 196 2.25 (1.88–2.48) 2.41 (2.00–2.81) ns
  1. Difference of imaging marker was assessed by Mann-Whitney U-test, medians are presented together with IQRs
  2. ns not significant, ABPI ankle brachial pressure index, CCA common carotid artery, IMT intima media thickness, PWV pulse wave velocity, RHI reactive hyperemia index