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Table 5 Association between plasma renin levels and measures of atherosclerosis burden, arterial stiffness and endothelial function

From: Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes

   T2D Non-T2D
ABPI r −0.19 −0.15
95 % CI (−0.26, −0.13) (−0.23, −0.06)
pCor 7.7E-09 0.001
r2 0.14 0.20
pReg 7.4E-09 0.006
CCA IMT r 0.15 0.19
95 % CI (0.08, 0.21) (0.10, 0.27)
pCor 1.2E-05 4.7E-05
r2 0.15 0.29
pReg 0.015 ns
Bulb IMT r 0.27 0.30
95 % CI (0.20, 0.33) (0.21, 0.38)
pCor 1.1E-14 1.8E-10
r2 0.22 0.28
pReg 8.7E-07 0.001
Plaque area r 0.25 0.27
95 % CI (0.18, 0.32) (0.17, 0.36)
pCor 6.4E-12 1.4E-07
r2 0.25 0.31
pReg 3.3E-09 3.70E-05
PWV r 0.08 0.18
95 % CI (0.01, 0.15) (0.09, 0.27)
pCor 0.029 1.2E-04
r2 0.33 0.36
pReg ns ns
RHI r −0.14 −0.14
95 % CI (−0.21, −0.08) (−0.23, −0.05)
pCor 1.8E-05 0.002
r2 0.08 0.15
pReg 0.025 ns
  1. r Pearson correlation coefficient, 95 % CI 95 % confidence interval for r, pCor p-value for correlation significance, r2 proportion of variation explained by linear regression model adjusted for age, gender, total cholesterol, HDL systolic blood pressure, smoking, and study center, pReg p-value for significance of renin coefficient in this model; data of imaging variables has been log2-transformed to resemble normal distribution, ABPI ankle brachial pressure index, CCA common carotid artery, IMT intima media thickness, PWV pulse wave velocity, RHI reactive hyperemia index