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Table 5 Association between plasma renin levels and measures of atherosclerosis burden, arterial stiffness and endothelial function

From: Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes

  

T2D

Non-T2D

ABPI

r

−0.19

−0.15

95 % CI

(−0.26, −0.13)

(−0.23, −0.06)

pCor

7.7E-09

0.001

r2

0.14

0.20

pReg

7.4E-09

0.006

CCA IMT

r

0.15

0.19

95 % CI

(0.08, 0.21)

(0.10, 0.27)

pCor

1.2E-05

4.7E-05

r2

0.15

0.29

pReg

0.015

ns

Bulb IMT

r

0.27

0.30

95 % CI

(0.20, 0.33)

(0.21, 0.38)

pCor

1.1E-14

1.8E-10

r2

0.22

0.28

pReg

8.7E-07

0.001

Plaque area

r

0.25

0.27

95 % CI

(0.18, 0.32)

(0.17, 0.36)

pCor

6.4E-12

1.4E-07

r2

0.25

0.31

pReg

3.3E-09

3.70E-05

PWV

r

0.08

0.18

95 % CI

(0.01, 0.15)

(0.09, 0.27)

pCor

0.029

1.2E-04

r2

0.33

0.36

pReg

ns

ns

RHI

r

−0.14

−0.14

95 % CI

(−0.21, −0.08)

(−0.23, −0.05)

pCor

1.8E-05

0.002

r2

0.08

0.15

pReg

0.025

ns

  1. r Pearson correlation coefficient, 95 % CI 95 % confidence interval for r, pCor p-value for correlation significance, r2 proportion of variation explained by linear regression model adjusted for age, gender, total cholesterol, HDL systolic blood pressure, smoking, and study center, pReg p-value for significance of renin coefficient in this model; data of imaging variables has been log2-transformed to resemble normal distribution, ABPI ankle brachial pressure index, CCA common carotid artery, IMT intima media thickness, PWV pulse wave velocity, RHI reactive hyperemia index
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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