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Table 1 Clinical characteristics of the study cohort

From: Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes

  T2D with CVD T2D without CVD Non-T2D without CVD Non-T2D with CVD
N 458 527 270 245
Male sex, n(%) 331 (72) 324 (61) 163 (60) 161 (66)
Age, years 69.3 (7.8) 66.2 (8.8) 66.4 (9.1) 67.9 (9.2)
T2D Duration, years 12.2 (8.8) 9.1 (6.9)
BMI, kg/m2 30.1 (4.9) 30.8 (5.5) 27.0 (4.0) 27.6 (4.1)
Medication
 Statin use, n(%) 401 (88) 321 (61) 97 (36) 171 (70)
 Anti-hypertensive treatment use, n(%) 419 (92) 352 (67) 129 (48) 172 (70)
Blood pressure
 SBP, mmHg 138 (20.0) 136 (17.6) 132 (17.2) 134 (16.0)
 DBP, mmHg 76 (10.3) 78 (9.8) 77 (9.4) 77 (9.2)
 Pulse pressure, mmHg 62.6 (16.2) 58.2 (13.1) 54.5 (12.5) 57.2 (14.2)
Metabolic factors
 HbA1c, mmol/mol
 %
58.8 (13.9)
8.0 (5.0)
56.6 (13.0)
7.9 (10.0)
38.4 (3.9)
5.8 (2.3)
39.8 (4.7)
5.8 (0.5)
 Tot Cholesterol, mmol/l 3.92 (0.9) 4.38 (1.0) 5.03 (1.1) 4.47 (1.1)
 HDL, mmol/l 1.19 (0.35) 1.32 (0.38) 1.51 (0.44) 1.42 (0.40)
 LDL, mmol/l 2.06 (0.74) 2.42 (0.91) 3.01 (0.94) 2.52 (0.88)
 Triglycerides, mmol/l 1.68 (0.94) 1.62 (0.92) 1.30 (0.65) 1.37 (0.70)
Renal function
 Creatinine, serum, μmol/l 93.4 (32.2) 80.0 (20.6) 81.3 (18.5) 83.3 (19.3)
 ACR, mg/mmol 9.48 (37.4) 4.14 (16.5) 3.23 (22.7) 3.38 (15.3)
 eGFR 60.8 (20.3) 71.3 (19.4) 69.6 (17.7) 66.9 (18.9)
  1. Binary variables are reported as n(%) and quantitative data are reported as mean (SD)
  2. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HDL high-density lipoprotein, LDL low-density lipoprotein, ACR albumin creatinine ratio, eGFR estimated glomerular filtration rate