Table 1 Clinical characteristics of the study cohort
From: Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes
T2D with CVD | T2D without CVD | Non-T2D without CVD | Non-T2D with CVD | |
|---|---|---|---|---|
N | 458 | 527 | 270 | 245 |
Male sex, n(%) | 331 (72) | 324 (61) | 163 (60) | 161 (66) |
Age, years | 69.3 (7.8) | 66.2 (8.8) | 66.4 (9.1) | 67.9 (9.2) |
T2D Duration, years | 12.2 (8.8) | 9.1 (6.9) | – | – |
BMI, kg/m2 | 30.1 (4.9) | 30.8 (5.5) | 27.0 (4.0) | 27.6 (4.1) |
Medication | ||||
Statin use, n(%) | 401 (88) | 321 (61) | 97 (36) | 171 (70) |
Anti-hypertensive treatment use, n(%) | 419 (92) | 352 (67) | 129 (48) | 172 (70) |
Blood pressure | ||||
SBP, mmHg | 138 (20.0) | 136 (17.6) | 132 (17.2) | 134 (16.0) |
DBP, mmHg | 76 (10.3) | 78 (9.8) | 77 (9.4) | 77 (9.2) |
Pulse pressure, mmHg | 62.6 (16.2) | 58.2 (13.1) | 54.5 (12.5) | 57.2 (14.2) |
Metabolic factors | ||||
HbA1c, mmol/mol % | 58.8 (13.9) 8.0 (5.0) | 56.6 (13.0) 7.9 (10.0) | 38.4 (3.9) 5.8 (2.3) | 39.8 (4.7) 5.8 (0.5) |
Tot Cholesterol, mmol/l | 3.92 (0.9) | 4.38 (1.0) | 5.03 (1.1) | 4.47 (1.1) |
HDL, mmol/l | 1.19 (0.35) | 1.32 (0.38) | 1.51 (0.44) | 1.42 (0.40) |
LDL, mmol/l | 2.06 (0.74) | 2.42 (0.91) | 3.01 (0.94) | 2.52 (0.88) |
Triglycerides, mmol/l | 1.68 (0.94) | 1.62 (0.92) | 1.30 (0.65) | 1.37 (0.70) |
Renal function | ||||
Creatinine, serum, μmol/l | 93.4 (32.2) | 80.0 (20.6) | 81.3 (18.5) | 83.3 (19.3) |
ACR, mg/mmol | 9.48 (37.4) | 4.14 (16.5) | 3.23 (22.7) | 3.38 (15.3) |
eGFR | 60.8 (20.3) | 71.3 (19.4) | 69.6 (17.7) | 66.9 (18.9) |