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Table 3 Multivariate analysis of the associations between acute kidney injury and the clinical findings

From: The serum heart-type fatty acid-binding protein (HFABP) levels can be used to detect the presence of acute kidney injury on admission in patients admitted to the non-surgical intensive care unit

 

AKI

Class I/F

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

OR

95 % CI

p value

OR

95 % CI

p value

OR

95 % CI

p value

OR

95 % CI

p value

Quartiles of H-FABP

 Q1 (H-FABP≦6.2)

1.000

  

1.000

  

1.000

  

1.000

  

 Q2 (6.3≦H-FABP≦11.6)

2.453

1.095– 5.498

0.029

3.743

1.693–8.274

0.001

2.585

0.492–13.584

0.262

3.194

0.582–17.523

0.181

 Q3 (11.7≦H-FABP≦27.8)

5.030

2.311–10.947

<0.001

9.427

4.124–21.548

<0.001

5.938

1.288–27.374

0.022

5.155

1.030–25.790

0.046

 Q4 (27.9≦H-FABP)

12.778

5.774 –28.777

<0.001

28.000

11.245–69.720

<0.001

33.975

8.009–144.122

<0.001

22.978

4.814 –109.668

<0.001

Adjusting Factors

 Chronic kidney disease

1.196

0.786–1.819

0.404

   

0.652

0.373–1.141

0.134

   

 Age (≧71 years old)

0.921

0.626–1.356

0.677

   

0.887

0.520–1.512

0.659

   

 MBP (≧102 mmHg)

0.260

0.171–0.393

<0.001

0.264

0.172–0.442

<0.001

0.140

0.067–0.290

<0.001

0.191

0.087–0.416

<0.001

 LVEF (≧51 %)

0.757

0.493–1.163

0.204

   

0.533

0.486–1.453

0.840

   

 Hemoglobin (≧12.7 g/dl)

0.681

0.461–1.006

0.053

   

0.259

0.138–0.483

<0.001

0.430

0.212–0.874

0.020

 Hs-TropT (≧0.048 ng/ml)

2.319

1.555–3.458

<0.001

0.736

0.428–1.265

0.267

4.035

2.160–7.536

<0.001

1.220

0.553–2.691

0.623

 Nt-ProBNP (≧2553 pg/ml)

1.665

1.126–2.462

0.011

0.824

0.497–1.366

0.452

2.325

1.322–4.091

0.003

1.023

0.500–2.094

0.950

  1. HR hazard ratio, CI confidence interval, H-FABP heart-type fatty acid binding, MBPmean blood pressure, LVEF left ventricular ejection fraction measured on echocardiography, Hs-TropT high-sensitivity troponin T, Nt-proBNP N-Terminal pro-brain-type natriuretic peptide