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Table 2 Clinical characteristics at presentation, coronary angiography and revascularisation procedures in the protocol and non-protocol treated groups

From: Safety of the primary percutaneous coronary intervention strategy combining pre-hospital prasugrel, enoxaparin and in-hospital bivalirudin in acute ST-segment elevation myocardial infarction

 

Protocol

Non-protocol

p-value

 

n = 99

n = 291

 

Anterior STEMI, n (%)

43 (43.4)

138 (47.4)

0.492

GRACE score, mean (SD)

112 (31)

124 (36)

0.002

CRUSADE score, mean (SD)

21 (13)

28(16)

<0.0001

Killip class > I, n (%)

8 (8.1)

62 (21.5)

0.003

Killip class IV, n (%)

2 (2.0)

13 (4.5)

0.270

eGFR ml/min, mean (SD)

103 (40)

90 (41)

0.009

Hemoglobin g/l, mean (SD)

135 (15)

133 (18)

0.283

Weight kg, mean (SD)

81 (16)

80 (17)

0.644

Angiography

 Radialis access, n (%)

33 (33.3)

77 (26.6)

0.196

 3VD, n (%)

14 (14.1)

56 (19.2)

0.253

 LMD, n (%)

2 (2.0)

16 (5.5)

0.154

 TIMI flow grade 0–1, n (%)

68 (70.1)

119 (57.2)

0.031

 TIMI flow grade 3, n (%)

15 (15.5)

58 (27.9)

0.018

 Normal findings or modest coronary artery disease

0 (0)

46 (16.0)

<0.0001

PCI, n (%)

99 (100)

205 (70.4)

<0.0001

 Use of stents (of all PCI), n (%)

91 (91.9)

187 (91.2)

0.838

 Use of DES (of stents), n (%)

13 (14.3)

24 (12.8)

0.738

 Thrombectomy (of all PCI), n (%)

53 (53.5)

68 (33.2)

0.001

 TIMI flow grade 0–1 post PCI, n (%)

0 (0)

8 (3.8)

0.053

 TIMI flow grade 3 post PCI, n (%)

89 (91.8)

182 (85.8)

0.143

CABG, n (%)

2 (2.0)

17 (5.8)

0.127

  1. eGFR glomerular filtration rate estimated by Cockcroft-Gault formula, 3VD three vessel coronary artery disease, LMD left main coronary artery disease, LAD-PCI percutaneous coronary intervention to left anterior descending artery, DES drug-eluting stent, CABG coronary artery bypass graft surgery