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Table 3 Echocardiographic data of diabetic and control subjects

From: Tissue Doppler imaging is a sensitive echocardiographic technique to detect subclinical systolic and diastolic dysfunction of both ventricles in type 1 diabetes mellitus

 

Diabetic partients (n = 53)

Healthy controls (n = 48)

p-value

LA/RA dimensions (mean ± SD)

   

 LA volume (ml)

57.78 ± 11.15

43.89 ± 7.97

<0.001

 LA volume/BSA (ml/m2)

29.44 ± 3.82

22.94 ± 3.25

<0.001

 RA area (cm2)

15.38 ± 2.15

12.69 ± 2.05

<0.001

 RA area/BSA (cm2/m2)

7.90 ± 0.95

6.61 ± 0.79

<0.001

LV dimensions (2D), LVEF (mean ± SD)

   

 IVS (cm)

0.92 ± 0.11

0.82 ± 0.09

<0.001

 LVIDd (cm)

4.61 ± 0.39

4.65 ± 0.42

0.638

 LVIDd/BSA (cm/m2)

2.38 ± 0.24

2.46 ± 0.21

0.106

 LVPW (cm)

0.93 ± 0.11

0.85 ± 0.09

<0.001

 LVEF (%)

66.57 ± 5.89

67.82 ± 5.08

0.324

RV dimensions (2D) and TAPSE (mean ± SD)

   

 RVD1 (cm)

3.49 ± 0.37

3.53 ± 0.94

0.786

 RVD1/BSA (cm/m2)

1.79 ± 0.21

1.87 ± 0.44

0.262

 RVD2 (cm)

2.72 ± 0.43

2.60 ± 0.38

0.211

 RVD3 (cm)

7.10 ± 0.88

7.1 ± 0.82

0.977

 TAPSE (cm)

2.73 ± 0.36

2.83 ± 0.26

0.154

Mitral PWD parameters (mean ± SD)

   

 E (m/s)

0.79 ± 0.16

0.74 ± 0.12

0.111

 A (m/s)

0.68 ± 0.13

0.58 ± 0.10

<0.001

 E/A

1.19 ± 0.25

1.33 ± 0.27

0.011

 DT (ms)

187.76 ± 45.1

163.56 ± 28.14

0.002

Tricuspid (t) PWD parameters (mean ± SD)

   

 Et (m/s)

0.52 ± 0.11

0.49 ± 0.07

0.208

 At (m/s)

0.44 ± 0.22

0.35 ± 0.06

0.007

 Et/At

1.27 ± 0.31

1.41 ± 0.24

0.015

 DT-t (ms)

214.26 ± 65.41

210.61 ± 48.87

0.796

LV TDI parameters (mean ± SD)

   

 S’ sept (cm/s)

8.46 ± 1.64

9.19 ± 1.19

0.012

 S’ lat (cm/s)

10.62 ± 2.23

11.22 ± 2.29

0.183

 E’ sept (cm/s)

8.89 ± 1.89

11.50 ± 2.41

<0.001

 A’ sept (cm/s)

9.74 ± 1.95

9.41 ± 1.68

0.378

 E’/A’ sept

0.94 ± 0.26

1.28 ± 0.42

<0.001

 E/E’sept

9.07 ± 1.86

6.65 ± 1.35

<0.001

 E’ lat (cm/s)

12.29 ± 2.58

15.30 ± 2.95

<0.001

 A’ lat (cm/s)

9.64 ± 1.97

9.17 ± 2.45

0.296

 E’/A’ lat

1.35 ± 0.48

1.81 ± 0.64

<0.001

 E/E’ lat

6.55 ± 1.16

4.96 ± 0.90

<0.001

 LV IVV (cm/s)

6.82 ± 2.22

7.18 ± 2.00

0.406

 LV IVA (cm/s2)

230.70 ± 61.26

283.32 ± 59.74

<0.001

 LV MPI

0.51 ± 0.10

0.49 ± 0.09

0.455

RV TDI parameters (mean ± SD)

   

 S’t (cm/s)

14.40 ± 2.50

14.38 ± 2.15

0.961

 E’t (cm/s)

13.56 ± 2.91

15.60 ± 2.99

0.001

 A’t (cm/s)

14.03 ± 3.59

12.09 ± 2.66

0.003

 E’/A’t

1.01 ± 0.26

1.35 ± 0.39

<0.001

 E/E’t

3.93 ± 1.04

3.27 ± 0.57

<0.001

 RV IVV (cm/s)

10.82 ± 2.62

11.98 ± 2.81

0.045

 RV IVA (cm/s2)

275.48 ± 68.08

316.86 ± 80.95

0.011

 RV MPI

0.31 ± 0.07

0.29 ± 0.07

0.335

  1. LA left atrium, RA right atrium, BSA body surface area, LV left ventricle, LVEF left ventricular ejection fraction, IVS interventricular septum, LVIDd left ventricular internal dimension at end diastole, LVPW left ventricular posterior wall thickness, RV right ventricle, TAPSE tricuspid anular plane systolic excursion, RVD1 right ventricular basal diameter, RVD2 right ventricular mid-cavity diameter, RVD3 right ventricular longitudinal diameter; E peak early mitral filling velocity, A peak late mitral filling velocity, DT peak early mitral velocity deceleration time, Et peak early tricuspid filling velocity, At peak late tricuspid filling velocity, DT-t peak early tricuspid velocity deceleration time, S’sept peak systolic mitral annular velocity at the septal part of mitral annulus, S’lat peak systolic mitral annular velocity at the lateral part of mitral annulus, E’sept peak early diastolic mitral annular velocity at the septal part of mitral annulus, E’lat peak early diastolic mitral annular velocity at the lateral part of mitral annulus, A’sept peak late diastolic mitral annular velocity at the septal part of mitral annulus, A’lat peak late diastolic mitral annular velocity at the lateral part of mitral annulus, S’t peak systolic tricuspid annular velocity, E’t peak early diastolic tricuspid annular velocity, A’t peak late diastolic tricuspid annular velocity, IVV peak myocardial velocity during isovolumetric contraction, IVA myocardial acceleration during isovolumetric contraction, MPI myocardial performance index