Outcome | Thrombus aspiration N = 3621 | PCI alone N = 3623 | Hazard ratio (95 % CI) | P-value |
---|---|---|---|---|
Efficacy up to 180 days | ||||
Cardiovascular (CV) death | 125 (3.5 %) | 133 (3.7 %) | 0.94 (0.74-1.20) | 0.62 |
All cause death | 145 (4.0 %) | 156 (4.3 %) | 0.93 (0.74-1.17) | 0.52 |
Rehospitalisation for new myocardial infarction (Rehosp-MI) | 63 (1.7 %) | 70 (1.9 %) | 0.90 (0.64-1.26) | 0.53 |
Definite stent thrombosis (ST) | 20 (0.6 %) | 26 (0.7 %) | 0.77 (0.42-1.37) | 0.37 |
Target vessel revascularization (TVR) | 130 (3.6 %) | 144 (4.0 %) | 0.90 (0.71-1.14) | 0.38 |
Cardiogenic chock or new hospitalisation with heart failure (HF) | 176 (4.9 %) | 186 (5.1 %) | 0.95 (0.77-1.16) | 0.59 |
CV death, cardiogenic shock, Rehosp-MI or new heart failure (HF)a | 316 (8.7 %) | 338 (9.3 %) | 0.93 (0.80-1.09) | 0.36 |
Cardiovascular death, cardiogenic shock, Rehosp-MI, new HF, definite ST or TVR | 409 (11.3 %) | 448 (12.4 %) | 0.91 (0.79-1.04) | 0.15 |
Efficacy during follow-up (median 25 months) | ||||
Cardiovascular death | 215 (5.9 %) | 229 (6.3 %) | 0.94 (0.78 - 1.13) | 0.51 |
Cardiovascular death, cardiogenic shock, Rehosp-MI or new HFa | 483 (13.3 %) | 521 (14.4 %) | 0.92 (0.82-1.05) | 0.21 |
Cardiovascular death, cardiogenic shock, Rehosp-MI, new HF, definite ST or TVR | 615 (17.0 %) | 678 (18.7 %) | 0.90 (0.81-1.00) | 0.058 |
Safety | ||||
Stroke up to 30 days | 24 (0.7 %) | 27 (0.7 %) | 0.89 (0.51-1.54) | 0.68 |
Stroke up to 180 days | 42 (1.2 %) | 45 (1.2 %) | 0.93 (0.61-1.42) | 0.75 |
Stroke until follow up (median 25 months) | 89 (2.5 %) | 89 (2.5 %) | 1.00 (0.75-1.34) | 0.99 |
Net-benefit up to 180 days | ||||
Cardiovascular death, cardiogenic shock, Rehosp-MI, new HF, or strokeb | 343 (9.5 %) | 371 (10.2 %) | 0.92 (079-1.07) | 0.27 |
Cardiovascular death, cardiogenic shock, Rehosp-MI, new HF, stroke, definite ST or TVRc | 436 (12.0 %) | 479 (13.2 %) | 0.90 (0.79-1.03) | 0.12 |
Net-benefit during follow-up (median 25 months) | ||||
Cardiovascular death, cardiogenic shock, Rehosp-MI, new HF, or strokeb | 545 (15.1 %) | 582 (16.1 %) | 0.93 (0.83-1.05) | 0.24 |
Cardiovascular death, cardiogenic shock, Rehosp-MI, new HF, stroke, definite ST or TVRc | 677 (18.7 %) | 736 (20.3 %) | 0.91 (0.82-1.01) | 0.08 |