Table 3 Short Form-36 (SF-36) for conventionally treated (CTR) and patients whose treatment was guided by BNP and for responders and non-responders at study start and at study end. Responder defined as a patient with a BNP under 300 ng/l and/or a decrease in BNP of at least 40 percent in week 16 of follow-up, compared to study start
Study start | Study end | Study start | Study end | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |||||||||
CTR group | BNP group | p | CTR group | BNP group | p | Responders | Non-responders | p | Responders | Non-responders | p | |
n = 127 | n = 131 | n = 98 | n = 100 | n = 78 | n = 53 | n = 68 | n = 32 | |||||
SF-36 | ||||||||||||
PF | 46.4 (±27) | 45.3 (±26) | 0.80 | 54.8 (±26) | 55.2 (±27) | 0.78 | 51.3 (±25) | 36.5 (±24) | 0.001 | 52.7 (±26) | 42.3 (±23) | 0.055 |
RP | 19.1 (±33) | 28.4 (±38) | 0.06 | 39.8 (±44) | 46.4 (±44) | 0.21 | 32.4 (±38) | 22.6 (±37) | 0.15 | 33.5 (±44) | 22.7 (±38) | 0.20 |
BP | 56.4 (±31) | 60.6 (±29) | 0.26 | 65.8 (±29) | 69.6 (±29) | 0.39 | 62.7 (±29) | 57.4 (±29) | 0.32 | 64.6 (±29) | 64.2 (±30) | 0.95 |
GH | 47.1 (±20) | 48.5 (±18) | 0.45 | 50.9 (±20) | 53.8 (±19) | 0.51 | 51.8 (±18) | 43.8 (±17) | 0.01 | 52.2 (±20) | 45.5 (±17) | 0.07 |
VT | 43.1 (±22) | 42.0 (±21) | 0.61 | 50.2 (±25) | 51.9 (±22) | 0.63 | 43.3 (±22) | 40.2 (±19) | 0.40 | 42.5 (±25) | 43.0 (±18) | 0.91 |
SF | 62.4 (±25) | 67.8 (±25) | 0.10 | 75.1 (±24) | 73.8 (±25) | 0.60 | 72.6 (±25) | 60.5 (±23) | 0.006 | 72.6 (±24) | 62.5 (±22) | 0.056 |
RE | 41.1 (±45) | 49.0 (±45) | 0.19 | 54.5 (±44) | 57.1 (±42) | 0.75 | 52.8 (±44) | 43.4 (±45) | 0.24 | 55.7 (±44) | 44.8 (±45) | 0.26 |
MH | 70.0 (±20) | 69.6 (±19) | 0.82 | 74.1 (±19) | 76 (±17) | 0.61 | 70.1 (±18) | 68.8 (±20) | 0.69 | 70.1 (±19) | 69.5 (±19) | 0.87 |
PCS | 31.5 (±11) | 32.7 (±11) | 0.24 | 35.6 (±11) | 37.8 (±12) | 0.18 | 34.9 (±10) | 29.6 (±11) | 0.007 | 35.5 (±11) | 31.6 (±11) | 0.09 |
MCS | 42.7 (±12) | 43.6 (±11) | 0.60 | 46.0 (±11) | 46.5 (±10) | 0.87 | 44.3 (±11) | 42.7 (±11) | 0.45 | 44.3 (±11) | 43.1 (±11) | 0.63 |