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Table 3 Peak regional and global strain and strain rate of rats at 6 weeks measured through STE. Views were detected from the parasternal short axis at the mid papillary muscle level

From: Left ventricular deformation associated with cardiomyocyte Ca2+ transients delay in early stage of low-dose of STZ and high-fat diet induced type 2 diabetic rats

   

Strain

Strain Rate

   

Control Rats

Model Rats

P

Control Rats

Model Rats

P

(n = 8)

(n = 8)

(n = 8)

(n = 8)

Diastolic

Radial

AFW

−36.04 ± 12.68

−9.05 ± 10.10

<0.001#

−11.06 ± 4.14

−7.63 ± 1.99

0.1144

LW

−24.86 ± 4.25

−10.16 ± 7.58

<0.001#

−9.62 ± 2.87

−5.79 ± 1.37

0.0087#

PW

−25.03 ± 11.78

−10.39 ± 9.79

0.0076#

−8.37 ± 3.04

−5.58 ± 1.77

0.0299*

IFW

−29.12 ± 13.97

−11.21 ± 12.85

0.0126*

−8.52 ± 2.03

−6.64 ± 1.78

0.0453*

PS

−22.88 ± 12.69

−6.24 ± 4.63

0.0031#

7.07 ± 2.99

−5.78 ± 2.03

0.2376

AS

−21.64 ± 13.99

−4.24 ± 4.75

0.0209*

−6.89 ± 2.27

−7.07 ± 1.71

0.7496

Average

−26.63 ± 9.04

−7.05 ± 5.97

<0.001#

−9.13 ± 2.51

−6.62 ± 1.16

0.0304*

Circumferential

AFW

26.29 ± 12.24

1.43 ± 0.99

<0.001#

7.64 ± 2.77

4.44 ± 2.45

0.0417*

LW

27.35 ± 13.97

2.95 ± 2.63

<0.001#

7.31 ± 2.73

3.14 ± 2.02

0.0045#

PW

31.07 ± 11.35

0.80 ± 0.34

<0.001#

8.06 ± 1.71

5.36 ± 1.92

0.0094#

IFW

29.44 ± 19.96

0.81 ± 1.04

<0.001#

10.53 ± 6.33

5.74 ± 2.93

0.0789

PS

29.77 ± 19.52

0.90 ± 0.46

0.0010#

8.10 ± 2.44

8.75 ± 6.02

0.7597

AS

21.32 ± 8.25

0.66 ± 0.40

<0.001#

6.25 ± 2.31

5.96 ± 1.80

0.9022

Average

29.57 ± 14.35

1.25 ± 0.69

<0.001#

7.98 ± 2.37

5.65 ± 2.55

0.1008

Systolic

Radial

AFW

38.72 ± 10.04

23.92 ± 9.61

0.0537

9.79 ± 6.05

4.76 ± 1.79

0.0407*

LW

26.89 ± 14.94

19.44 ± 8.94

0.2461

7.76 ± 3.56

4.04 ± 1.83

0.0229*

PW

25.87 ± 14.55

19.77 ± 10.01

0.3456

7.15 ± 1.54

3.97 ± 1.75

0.0012#

IFW

24.83 ± 10.11

17.33 ± 10.48

0.1671

8.20 ± 3.16

4.30 ± 2.44

0.0158*

PS

16.91 ± 6.25

10.63 ± 8.49

0.1144

6.93 ± 1.84

4.13 ± 2.82

0.0211*

AS

25.73 ± 19.00

19.19 ± 7.47

0.3801

5.71 ± 2.15

4.02 ± 2.33

0.1817

Average

26.13 ± 9.75

18.12 ± 5.56

0.0630

8.67 ± 2.59

4.23 ± 1.94

0.0022#

Circumferential

AFW

−23.39 ± 8.39

−15.77 ± 9.22

0.1495

−6.74 ± 2.81

−4.86 ± 3.78

0.3395

LW

−20.64 ± 6.31

−10.34 ± 12.62

0.0584

−6.54 ± 2.31

−2.37 ± 1.29

0.0010#

PW

−21.98 ± 4.79

−19.57 ± 8.18

0.5102

−7.11 ± 1.41

−5.26 ± 1.24

0.0238*

IFW

−24.04 ± 7.22

−21.58 ± 10.30

0.3488

−7.42 ± 2.52

−5.45 ± 1.62

0.1154

PS

−23.00 ± 3.23

−27.95 ± 10.02

0.2074

−8.25 ± 2.92

−7.68 ± 4.87

0.8873

AS

−19.84 ± 7.12

−24.72 ± 8.53

0.1340

−5.61 ± 1.78

−6.60 ± 3.31

0.3478

Average

−22.01 ± 3.87

−19.99 ± 7.67

0.5314

−6.95 ± 1.98

−5.65 ± 3.18

0.4198

  1. Data are presented as mean ± SD. Abbreviations: AFW anterior free wall, LW lateral wall, PW posterior wall, IFW inferior free wall, PS post septum, AS anterior septum
  2. *Compared to control group, P<0.05; #Compared to control group, P<0.01