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Table 4 In vitro effect of atorvastatin on FoxP3 expression in CD4+ subsets obtained from healthy subjects

From: Relationship between regulatory T cells subsets and lipid profile in dyslipidemic patients: a longitudinal study during atorvastatin treatment

  Atorvastatin (μM)
  PHA 1 5 10
CD4 + FoxP3+ (%) 78.17 ± 9.03 80.30 ± 4.35 72.33 ± 9.77 60.79 ± 9.39*
CD4 + CD25 + FoxP3+ (%) 78.81 ± 8.23 80.46 ± 1.32 74.17 ± 8.48 64.28 ± 7.63*
CD4 + CD25-FoxP3+ (%) 19.56 ± 12.64 10.20 ± 3.82 17.46 ± 12.07 11.80 ± 9.65
  1. Values are expressed as mean ± SD; P values were assessed by ANOVA followed by Dunnett comparison; * = P < 0.05 vs respective control