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Table 4 In vitro effect of atorvastatin on FoxP3 expression in CD4+ subsets obtained from healthy subjects

From: Relationship between regulatory T cells subsets and lipid profile in dyslipidemic patients: a longitudinal study during atorvastatin treatment

 

Atorvastatin (μM)

 

PHA

1

5

10

CD4 + FoxP3+ (%)

78.17 ± 9.03

80.30 ± 4.35

72.33 ± 9.77

60.79 ± 9.39*

CD4 + CD25 + FoxP3+ (%)

78.81 ± 8.23

80.46 ± 1.32

74.17 ± 8.48

64.28 ± 7.63*

CD4 + CD25-FoxP3+ (%)

19.56 ± 12.64

10.20 ± 3.82

17.46 ± 12.07

11.80 ± 9.65

  1. Values are expressed as mean ± SD; P values were assessed by ANOVA followed by Dunnett comparison; * = P < 0.05 vs respective control