Characteristics | Total sample | Low variability | High variability | P |
---|---|---|---|---|
(n = 305) | (n = 148) | (n = 157) | ||
Age | 57.3 ± 6.2 | 57.9 ± 6.4 | 57.5 ± 6.0 | 0.565 |
Female gender | 196 (64.3) | 99 (66.9) | 97 (61.8) | 0.354 |
Caucasian | 207 (68.3) | 99 (66.9) | 110 (70.1) | 0.334 |
Duration of diabetes (years) | 10 (5 – 16) | 10 (5 – 16) | 10 (5 – 17) | 0.466 |
Weight | 78.3 ± 12.8 | 79.6 ± 13.6 | 77.3 ± 12.1 | 0.116 |
BMI (kg/m2) | 30.1 ± 3.8 | 30.7 ± 3.9 | 29.6 ± 3.7 | 0.013 |
Waist circumference | 102 ± 9 | 103 ± 10 | 101 ± 91 | 0.203 |
Neck circumference | 38.5 ± 3.5 | 38.5 ± 3.3 | 38.6 ± 3.7 | 0.874 |
Smoking | ||||
No | 163 (33.4) | 81 (55.9) | 82 (52.2) | 0.803 |
Yes | 38 (12.6) | 18 (12.4) | 20 (12.7) | |
Former | 101 (54) | 46 (31.7) | 55 (35.0) | |
With any previous cardiovascular comorbiditya | 70 (23) | 31 (20.9) | 39 (24.8) | 0.404 |
Abnormal albuminuriab | 88 (28.9) | 43 (29.0) | 45 (28.7) | 0.520 |
Myocardial infarction | 38 (12.6) | 16 (11.0) | 22 (14.1) | 0.410 |
Coronary artery bypass grafting | 13 (4.3) | 4 (2.8) | 9 (5.8) | 0.199 |
PCI | 25 (8.3) | 9 (6.3) | 16 (10.3) | 0.210 |
Heart failure | 26 (8.7) | 15 (10.3) | 11 (7.1) | 0.318 |
Stroke | 28 (9.5) | 19 (13.5) | 9 (5.8) | 0.024 |
Medications | ||||
Insulin | 143 (47.2) | 58 (39.5) | 85 (54.5) | 0.009 |
1 Antihypertensive drug | 50 (16.4) | 22 (14.9) | 28 (17.8) | 0.537 |
2 Antihypertensive drug | 87 (28.5) | 38 (25.7) | 49 (31.2) | 0.311 |
≥3 Antihypertensive drug | 168 (55.1) | 88 (59.5) | 80 (51) | 0.167 |
Antiplatelet | 199 (65.9) | 101 (68.7) | 98 (63.2) | 0.315 |
Statins | 210 (69.8) | 113 (76.9) | 97 (63) | 0.009 |
Laboratory characteristics | ||||
HbA1c (%) | 8.2 ± 1.9 | 8.2 ± 1.9 | 8.3 ± 1.9 | 0.743 |
Fasting plasma glucose (mg/dL) | 159.3 ± 72.4 | 162.2 ± 74.8 | 156.7 ± 70.4 | 0.533 |
Total cholesterol (mg/dL) | 178.8 ± 42.4 | 176.6 ± 38.7 | 180.7 ± 45.6 | 0.426 |
HDL cholesterol (mg/dL) | 41.9 ± 11.8 | 42.1 ± 12.3 | 41.8 ± 11.4 | 0.793 |
Triglycerides (mg/dL) | 155 (103.8 – 234) | 152 (103 – 216) | 163 (104 – 248) | 0.534 |
GFR (mL/min/1.73 m2) | 90.4 ± 26.8 | 89.1 ± 26.4 | 91.7 ± 27.2 | 0.401 |