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Table 3 Cost-effectiveness results over a lifetime time horizon (adapted from Table 2 in US analysis)

From: Cost-effectiveness of fondaparinux versus enoxaparin in non-ST-elevation acute coronary syndrome in Canada (OASIS-5)

 

Enoxaparin

Fondaparinux

ICER

Patient with average characteristics

   

 Expected cost

$110,477

$110,661

$4293

 Expected quality-adjusted life years

6.37

6.42

 Probablity most cost-effective at a threshold of $50,000 per QALY

 

96 %

 Probability of cost-saving

 

42 %

Patient at low risk of composite event over 180 days (2.5th percentile)

   

 Expected cost

$164,824

$164,836

$661

 Expected quality-adjusted life years

11.01

11.03

 Probability most cost-effective at a threshold of $50,000 per QALY

 

83 %

 Probability of cost-saving

 

48 %

Patient at high risk of composite event over 180 days (97.5th percentile)

   

 Expected cost

$70,846

$71,299

$4666

 Expected quality-adjusted life years

3.37

3.47

 Probability most cost-effective at a threshold of $50,000 per QALY

 

100 %

 Probability of cost-saving

 

34 %