Circulating concentrations of endothelin-1 predict coronary heart disease in women but not in men: a longitudinal observational study in the Vara-Skövde Cohort

Table 3 Predictive value of baseline circulating endothelin-1 levels on CHD in men and women in the Vara-Skövde cohort

Men (n = 1350)			Women (n = 1395)
HR	CI	p	HR	CI	p
Crude
0.98	0.8–1.2	0.818	1.64	1.2–2.3	0.003
Adjusted for age
0.98	0.8–1.2	0.854	1.51	1.1–2.1	0.015
Adjusted for age, HOMA-IR, apoB/apoA1 and smoking
0.88	0.7–1.1	0.272	1.53	1.1–2.1	0.024

Cox-regression analysing the hazard ratio for CHD during follow-up time for changes of endothelin-1 concentrations with 1 pg/ml
HR hazard ratio, CI confidence interval, ApoB/apoA1 apolipoprotein B/apolipoprotein A1, HOMA-IR homeostatic model assessment of insulin resistance

ISSN: 1471-2261