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Table 2 Associations between circulating endothelin-1 levels and selected variables at baseline in men and women from the Vara-Skövde cohort

From: Circulating concentrations of endothelin-1 predict coronary heart disease in women but not in men: a longitudinal observational study in the Vara-Skövde Cohort

 

Men (n = 1350)

Women (n = 1395)

 

β

P

β

P

Age

0.029

0.290

0.090

0.001

BMI

0.025

0.343

0.015

0.563

WHR

0.023

0.237

0.001

0.999

HOMA-IR

0.066

0.016

0.031

0.262

Systolic BP

0.026

0.392

−0.029

0.386

Diastolic BP

0.012

0.663

−0.010

0.854

S-HDL

0.010

0.695

0.065

0.015

S-LDL

0.030

0.154

0.040

0.354

ApoB/apoA1

−0.064

0.018

0.001

0.999

Triglycerides

0.029

0.289

−0.018

0.697

CRP

−0.020

0.437

0.015

0.542

Glucose

0.026

0.352

−0.014

0.618

LTPA

−0.017

0.541

0.022

0.432

Smoking habits

0.007

0.776

0.018

0.524

Testosterone

−0.055

0.048

0.006

0.816

Estradiol

0.001

0.990

0.005

0.861

  1. Age-adjusted linear regression analysis to investigate the association between concentrations of endothelin-1 and factors related to coronary heart disease
  2. HOMA-IR homeostatic model assessment of insulin resistance, BMI body mass index, WHR waist/hip ratio, BP blood pressure, HDL high-density lipoprotein, LDL low-density lipoprotein, ApoB/apoA1 apolipoprotein B/apolipoprotein A1, CRP C-reactive protein, LTPA leisure time physical activity