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Table 3 Predictors of mortality in univariate Cox proportional hazards regression model and multivariate Cox regression analysis

From: How low should we target the LDL goal to improve survival for acute coronary syndrome patients in Hong Kong?

Variable Hazard ratio 95 % CI p-value
Univariate Cox proportional hazards regression model of mortality
 Male sex 0.525 0.346–0.796 0.002
 Age at discharge 1.069 1.045–1.092 <0.001
 Active smoking status 0.511 0.284–0.920 0.025
 Past medical history of IHD or ACS 1.827 1.177–2.836 0.007
 Past medical history of CVA 2.755 1.688–4.498 <0.001
 Co-morbidity of hypertension 1.601 1.008–2.542 0.046
 Co-morbidity of heart failure 4.266 2.770–6.570 <0.001
 Co-morbidity of diabetes mellitus 1.786 1.174–2.715 0.007
 STEMI at index hospitalization 0.345 0.213–0.560 <0.001
 PCI done or planned during index hospitalization 0.185 0.108–0.318 <0.001
 CABG done or planned during index hospitalization 0.609 0.223–1.660 0.332
 Latest TG level before discharge 0.842 0.617–1.149 0.279
 Latest HDL-C level before discharge 0.674 0.298–1.521 0.342
 Latest LDL-C level before discharge 0.873 0.649–1.175 0.370
 Prescription of statins at discharge 0.285 0.188–0.433 <0.001
 Latest CK level before discharge > 2 × ULN 1.659 0.724–3.803 0.231
 Latest serum ALT level before discharge > 3 × ULN 6.491 2.371–17.770 <0.001
 First TG level 6 months after discharge 0.740 0.478–1.145 0.177
 First HDL-C level 6 months after discharge 0.875 0.402–1.905 0.737
 First LDL-C level 6 months after discharge 1.685 1.230–2.308 0.001
 Number of in-patient hospitalization due to cardiac reasons 1.076 1.034–1.120 <0.001
Predictors of mortality in multivariate Cox regression analysis
 Male sex 0.936 0.487–1.801 0.843
 Age at discharge 1.066 1.027–1.107 0.001
 Active smoking status 1.602 0.671–3.825 0.289
 Past medical history of IHD or ACS 0.493 0.237–1.023 0.057
 Past medical history of CVA 1.804 0.866–3.758 0.115
 Co-morbidity of hypertension 0.765 0.364–1.608 0.480
 Co-morbidity of heart failure 2.859 1.448–5.646 0.002
 Co-morbidity of diabetes mellitus 1.217 0.632–2.342 0.556
 STEMI at index hospitalization 0.318 0.157–0.645 0.002
 PCI done or planned during index hospitalization 0.468 0.203–1.075 0.074
 Prescription of statins at discharge 0.833 0.416–1.664 0.604
 Latest serum ALT level before discharge > 3 × ULN 0.961 0.113–8.116 0.971
 First TG level 6 months after discharge 0.695 0.384–1.260 0.231
 First LDL-C level 6 months after discharge 1.824 1.233–2.697 0.003
 Number of in-patient hospitalization due to cardiac reasons 1.010 0.928–1.100 0.814