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Table 3 Predictors of mortality in univariate Cox proportional hazards regression model and multivariate Cox regression analysis

From: How low should we target the LDL goal to improve survival for acute coronary syndrome patients in Hong Kong?

Variable

Hazard ratio

95 % CI

p-value

Univariate Cox proportional hazards regression model of mortality

 Male sex

0.525

0.346–0.796

0.002

 Age at discharge

1.069

1.045–1.092

<0.001

 Active smoking status

0.511

0.284–0.920

0.025

 Past medical history of IHD or ACS

1.827

1.177–2.836

0.007

 Past medical history of CVA

2.755

1.688–4.498

<0.001

 Co-morbidity of hypertension

1.601

1.008–2.542

0.046

 Co-morbidity of heart failure

4.266

2.770–6.570

<0.001

 Co-morbidity of diabetes mellitus

1.786

1.174–2.715

0.007

 STEMI at index hospitalization

0.345

0.213–0.560

<0.001

 PCI done or planned during index hospitalization

0.185

0.108–0.318

<0.001

 CABG done or planned during index hospitalization

0.609

0.223–1.660

0.332

 Latest TG level before discharge

0.842

0.617–1.149

0.279

 Latest HDL-C level before discharge

0.674

0.298–1.521

0.342

 Latest LDL-C level before discharge

0.873

0.649–1.175

0.370

 Prescription of statins at discharge

0.285

0.188–0.433

<0.001

 Latest CK level before discharge > 2 × ULN

1.659

0.724–3.803

0.231

 Latest serum ALT level before discharge > 3 × ULN

6.491

2.371–17.770

<0.001

 First TG level 6 months after discharge

0.740

0.478–1.145

0.177

 First HDL-C level 6 months after discharge

0.875

0.402–1.905

0.737

 First LDL-C level 6 months after discharge

1.685

1.230–2.308

0.001

 Number of in-patient hospitalization due to cardiac reasons

1.076

1.034–1.120

<0.001

Predictors of mortality in multivariate Cox regression analysis

 Male sex

0.936

0.487–1.801

0.843

 Age at discharge

1.066

1.027–1.107

0.001

 Active smoking status

1.602

0.671–3.825

0.289

 Past medical history of IHD or ACS

0.493

0.237–1.023

0.057

 Past medical history of CVA

1.804

0.866–3.758

0.115

 Co-morbidity of hypertension

0.765

0.364–1.608

0.480

 Co-morbidity of heart failure

2.859

1.448–5.646

0.002

 Co-morbidity of diabetes mellitus

1.217

0.632–2.342

0.556

 STEMI at index hospitalization

0.318

0.157–0.645

0.002

 PCI done or planned during index hospitalization

0.468

0.203–1.075

0.074

 Prescription of statins at discharge

0.833

0.416–1.664

0.604

 Latest serum ALT level before discharge > 3 × ULN

0.961

0.113–8.116

0.971

 First TG level 6 months after discharge

0.695

0.384–1.260

0.231

 First LDL-C level 6 months after discharge

1.824

1.233–2.697

0.003

 Number of in-patient hospitalization due to cardiac reasons

1.010

0.928–1.100

0.814