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Table 1 Clinical characteristics in patients with FMD <4.2 % and ≥4.2 %

From: Prognostic significance of endothelial dysfunction in patients undergoing percutaneous coronary intervention in the era of drug-eluting stents

 

FMD <4.2 % (n = 40 )

FMD ≥ 4.2 % (n = 40)

p

Age (years)

69.5 ± 7.1

69.4 ± 7.3

0.96

Female gender, n (%)

34 (85.0)

30 (75.0)

0.26

Body mass index

25.1 ± 3.4

23.6 ± 3.3

0.06

Diabetes mellitus, n (%)

23 (57.5)

22 (55.0)

0.82

Hypertension, n (%)

27 (65.7)

27 (67.5)

1.00

Dyslipidemia, n (%)

22 (55.0)

31 (77.5)

0.03

Current smoking, n (%)

10 (25.0)

11 (27.5)

0.80

Chronic renal insufficiency, n (%)

16 (40.0)

19 (47.5)

0.50

Previous PCI, n (%)

5 (12.5)

10 (25.0)

0.15

Previous myocardial infarction, n (%)

2 (5.0)

2 (5.0)

1.00

HDL cholesterol (mg/dl)

43.8 ± 11.2

49.3 ± 12.3

0.04

LDL cholesterol (mg/dl)

87.8 ± 28.1

88.1 ± 24.6

0.96

Triglycerides (mg/dl)

142.9 ± 73.6

113.7 ± 61.6

0.06

MDA-LDL cholesterol

97.9 ± 36.8 (n = 33)

82.2 ± 32.0 (n = 27)

0.62

Adiponectin

11.3 ± 5.2

12.0 ± 5.3

0.90

Medications

   

Aspirin, n (%)

40 (100)

38 (95.0)

0.15

Clopidogrel, n (%)

35 (87.5)

33 (82.5)

0.53

ACE inhibitor/ARB, n (%)

35 (87.5)

30 (75.0)

0.15

ARB, n (%)

31 (77.5)

25 (62.5)

0.22

ACE inhibitors, n (%)

4 (10.0)

5 (12.5)

0.99

Perindopril

2 (5.0)

1 (2.5)

0.99

Imidapril

2 (5.0)

4 (10.0)

0.67

Statins, n (%)

36 (90.0)

36 (90.0)

1.00

Atorvastatin

4 (10.0)

7 (17.5)

0.52

Rosuvastatin

18 (45.0)

16 (40.0)

0.82

Pitavastaitn

14 (35.0)

13 (32.5)

0.99

β-blockers, n (%)

21 (52.5)

25(62.5)

0.37

  1. Data are expressed as mean ± SD or number (percentage)
  2. FMD Flow-mediated dilation, PCI Percutaneous coronary intervention, HDL High-density lipoprotein, LDL low-density lipoprotein, MDA-LDL Malondialdehyde-modified low-density lipoprotein, ACE Angiotensin-converting enzyme, ARB Angiotensin II receptor blocker