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Table 1 Descriptive characteristics of valve surgery patients stratified by whether indication for surgery was RHD or non-RHD related [33]

From: A review of outcome following valve surgery for rheumatic heart disease in Australia

  All RHD-related Non-RHD P value
  N = 17227 N = 1384 N = 15843  
Age (years) (median (IQRa) 71.3(61.2 – 78.3) 59.7(50.9 – 71.4) 71.9(62.3 – 78.6) <0.001
Sex (% female) (95 % CI#) 37.3(36.6 – 38.1) 64.5(61.9 – 67.0) 35.0(34.2 – 35.7) <0.001
Indigenous status (% Aboriginal and Torres Strait Islander people) (95 % CI) 1.9(1.7 – 2.1) 12.6(10.9 – 14.4) 1.0(0.8 – 1.2) <0.001
Concomitant CABG (%, 95 % CI) 39.1(38.4 – 39.8) 21.2(19.1 – 23.5) 40.7(39.9 – 41.4) <0.001
Pre-operative comorbidities
 Diabetes (%, 95 % CI) 23.2(22.5 – 23.8) 20.3(18.2 – 22.5) 23.4(22.8 – 24.1) 0.009
 Chronic kidney disease (% eGFR < 60 mL/min/1.73 m2) (95 % CI)) 36.7(36.0 – 37.5) 31.2(28.8 – 33.7) 37.2(36.5 – 38.0) 0.814
 Hypertension (%, 95 % CI) 67.0(66.3 – 67.7) 53.0(50.3 – 55.7) 68.2(67.5 – 68.9) <0.001
 Previous smoking (%, 95 % CI) 53.1(52.3 – 53.8) 52.7(50.0 – 55.3) 53.1(52.3 – 53.9) 0.955
 Current smoking (%, 95 % CI) 16.0(15.2 – 16.7) 25.1(22.0 – 28.4) 15.2(14.5 – 16.0) <0.001
Pre-operative status
 NYHA classes III & IV (%, 95 % CI) 43.7(42.9 – 44.4) 53.7(51.0 – 56.4) 42.8(42.0 – 43.6) 0.351
 Atrial fibrillation (%, 95 % CI) 19.3(18.7 – 19.9) 40.5(37.9 – 43.2) 17.4(16.8 – 18.0) <0.001
 LVEF >45 % (%, 95 % CI) 81.2(80.6 – 81.8) 84.6(82.6 – 86.5) 80.9(80.3 – 81.5) 0.001
 LVEF 30 – 45 % (%, 95 % CI) 12.1(11.6 – 12.6) 10.9(9.3 – 12.7) 12.2(11.7 – 12.7) 0.154
 LVEF <30 % (%, 95 % CI) 4.3(4.0 – 4.6) 2.2(1.5 – 3.2) 4.5(4.2 – 4.8) <0.001
Previous procedures
 Valve surgery (%, 95 % CI) 6.4(6.1 – 6.8) 13.5(11.8 – 15.4) 5.8(5.4 – 6.2) <0.001
 Percutaneous balloon valvuloplasty (PBV) (%, 95 % CI) 4.9(4.3 – 5.6) 20.7(16.7 – 25.2) 3.3(2.8 – 4.0) <0.001
  1. aIQR – interquartile range, #95 % CI – 95 % confidence intervals