Fig. 2

FGF21 protected against ox-LDL and 7-KC induced macrophage apoptosis. a THP1 derived macrophages apoptosis was test by Annexin V and PI staining treated by ox-LDL in the presence or absence of FGF21 for 24 h. b Quantification of apoptosis cells in the FACS assay results of a. c THP1 derived macrophages apoptosis was test by Annexin V and PI staining treated by 7-KC in the presence or absence of FGF21 for 24 h. d Quantification of apoptosis cells in the FACS assay results of c. Data are presented as the mean ± S.E. of at least four independent experiments. *, p < 0.05, **, p < 0.01