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Table 1 Physiological parameters of mice in all groups

From: N-Acetyl Cysteine improves the diabetic cardiac function: possible role of fibrosis inhibition

  Initial weight Terminal weight HW HWI HR
(g) (g) (mg) (mg/kg, %) (bpm)
Control 24.32 ± 1.89 27.56 ± 2.33 168.12 ± 8.37 6.11 ± 0.22 446 ± 11
NAC only 23.44 ± 0.89 25.40 ± 0.54 160.40 ± 7.12 6.31 ± 0.21 448 ± 9
NAC1 23.22 ± 1.02 24.54 ± 0.65* 150.56 ± 7.07* 6.10 ± 0.18 445 ± 14
NAC3 23.67 ± 2.03 24.36 ± 1.91* 144.32 ± 13.42* 5.80 ± 0.25* 453 ± 21
NAC5 24.72 ± 1.31 24.45 ± 0.97* 144.00 ± 5.48* 5.78 ± 0.23* 440 ± 11
NAC7 24.86 ± 1.96 24.92 ± 1.83* 143.57 ± 8.94* 5.77 ± 0.14* 451 ± 19
DM 24.19 ± 1.60 24.84 ± 0.79* 138.00 ± 4.47* 5.56 ± 0.26* 441 ± 9
p valuea 0.347 0.940 0.668 0.066 0.61
  1. Notes: No significant differences were found between control and NAC only group; *Compared with control, p < 0.05; NAC treatment groups compared with DM group, p < 0.05; No significant difference was seen in initial weight and heart rate among all groups. a, ANOVA test among the NAC1, NAC3, NAC5 and NAC7 four groups, no significant difference was seen among the four groups. HW, heart weight; HWI, heart weight index; HR, heart rate. (n = 5 in each group)