Fig. 5
From: N-Acetyl Cysteine improves the diabetic cardiac function: possible role of fibrosis inhibition
Effects of NAC on high glucose induced fibroblast proliferation and collagen expression. (a) Cardiac fibroblast cells were cultured in 5.5 mM glucose (NG) and 25 mM glucose (HG) w/o 5 mM NAC. Viable cell numbers were calculated by CCK-8 kit. *p<0.05, n=3. (b) Col1a1 gene expression in cardiac fibroblasts cultured in serum free medium with 10 ng/ml TGFβ1 containing 5.5 mM glucose, 25 mM glucose with/o 5 mM NAC. *p<0.05, n=3. (c) CTGF gene expression in cardiac fibroblasts treated same as above. *p<0.05, n=3